• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

基于纳米材料的电化学免疫传感器

Nanomaterials-based Electrochemical Immunosensors.

作者信息

Zhang Zhenguo, Cong Yulin, Huang Yichun, Du Xin

机构信息

College of Life Sciences, Key Laboratory of Food Nutrition and Safety, Shandong Normal University, Jinan 250014, China.

出版信息

Micromachines (Basel). 2019 Jun 14;10(6):397. doi: 10.3390/mi10060397.

DOI:10.3390/mi10060397
PMID:31207970
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6630602/
Abstract

With the development of nanomaterials and sensor technology, nanomaterials-based electrochemical immunosensors have been widely employed in various fields. Nanomaterials for electrode modification are emerging one after another in order to improve the performance of electrochemical immunosensors. When compared with traditional detection methods, electrochemical immunosensors have the advantages of simplicity, real-time analysis, high sensitivity, miniaturization, rapid detection time, and low cost. Here, we summarize recent developments in electrochemical immunosensors based on nanomaterials, including carbon nanomaterials, metal nanomaterials, and quantum dots. Additionally, we discuss research challenges and future prospects for this field of study.

摘要

随着纳米材料和传感器技术的发展,基于纳米材料的电化学免疫传感器已在各个领域得到广泛应用。为了提高电化学免疫传感器的性能,用于电极修饰的纳米材料层出不穷。与传统检测方法相比,电化学免疫传感器具有操作简单、实时分析、灵敏度高、小型化、检测时间短和成本低等优点。在此,我们总结了基于纳米材料(包括碳纳米材料、金属纳米材料和量子点)的电化学免疫传感器的最新进展。此外,我们还讨论了该研究领域的挑战和未来前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/9c9e9ba66bb5/micromachines-10-00397-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/4f5760e89203/micromachines-10-00397-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/428afb1a7934/micromachines-10-00397-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/4e76e7f9a82f/micromachines-10-00397-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/22c9bca2e5dd/micromachines-10-00397-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/40971a4ab298/micromachines-10-00397-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/8582ba97f843/micromachines-10-00397-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/6c6a6f20e18b/micromachines-10-00397-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/09658902044b/micromachines-10-00397-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/d87696296e9a/micromachines-10-00397-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/8d13f4df3531/micromachines-10-00397-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/31324d73e945/micromachines-10-00397-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/9c9e9ba66bb5/micromachines-10-00397-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/4f5760e89203/micromachines-10-00397-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/428afb1a7934/micromachines-10-00397-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/4e76e7f9a82f/micromachines-10-00397-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/22c9bca2e5dd/micromachines-10-00397-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/40971a4ab298/micromachines-10-00397-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/8582ba97f843/micromachines-10-00397-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/6c6a6f20e18b/micromachines-10-00397-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/09658902044b/micromachines-10-00397-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/d87696296e9a/micromachines-10-00397-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/8d13f4df3531/micromachines-10-00397-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/31324d73e945/micromachines-10-00397-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7db/6630602/9c9e9ba66bb5/micromachines-10-00397-g012.jpg

相似文献

1
Nanomaterials-based Electrochemical Immunosensors.基于纳米材料的电化学免疫传感器
Micromachines (Basel). 2019 Jun 14;10(6):397. doi: 10.3390/mi10060397.
2
Nanomaterials for Electrochemical Immunosensing.用于电化学免疫传感的纳米材料。
Sensors (Basel). 2017 May 5;17(5):1041. doi: 10.3390/s17051041.
3
Graphene Quantum Dot-Based Electrochemical Immunosensors for Biomedical Applications.用于生物医学应用的基于石墨烯量子点的电化学免疫传感器。
Materials (Basel). 2019 Dec 23;13(1):96. doi: 10.3390/ma13010096.
4
Recent Advances in Electrochemical Immunosensors with Nanomaterial Assistance for Signal Amplification.电化学免疫传感器在纳米材料辅助下的信号放大技术的最新进展。
Biosensors (Basel). 2023 Jan 11;13(1):125. doi: 10.3390/bios13010125.
5
Electrochemical Sensors Based on Carbon Nanomaterial Used in Diagnosing Metabolic Disease.基于碳纳米材料的电化学传感器在代谢疾病诊断中的应用
Front Chem. 2020 Aug 11;8:651. doi: 10.3389/fchem.2020.00651. eCollection 2020.
6
Nanomaterial-Based Electrochemical Immunosensors for Clinically Significant Biomarkers.用于临床重要生物标志物的基于纳米材料的电化学免疫传感器
Materials (Basel). 2014 Jun 19;7(6):4669-4709. doi: 10.3390/ma7064669.
7
Immunosensors Based on Nanomaterials for Detection of Tumor Markers.基于纳米材料的用于检测肿瘤标志物的免疫传感器。
J Biomed Nanotechnol. 2018 Jan 1;14(1):44-65. doi: 10.1166/jbn.2018.2505.
8
Nanomaterial-Mediated Immunosensors and Their Performance in Detecting Tumor Markers.纳米材料介导的免疫传感器及其在肿瘤标志物检测中的性能。
Discov Med. 2024 Jul;36(186):1316-1333. doi: 10.24976/Discov.Med.202436186.122.
9
A New Approach in the Early Electrochemical Diagnosis of Hepatitis B Virus Infection using Carbon-based Nanomaterials.一种基于碳基纳米材料的乙肝病毒感染早期电化学诊断新方法。
Recent Pat Nanotechnol. 2025;19(2):166-182. doi: 10.2174/0118722105285022240311062943.
10
Electrochemical Biosensors for Detection of Foodborne Pathogens.用于检测食源性病原体的电化学生物传感器
Micromachines (Basel). 2019 Mar 28;10(4):222. doi: 10.3390/mi10040222.

引用本文的文献

1
Metal and metal oxide nanoparticle-assisted molecular assays for the detection of Salmonella.用于检测沙门氏菌的金属和金属氧化物纳米颗粒辅助分子分析方法。
Discov Nano. 2025 Apr 2;20(1):65. doi: 10.1186/s11671-025-04237-3.
2
Cutting-edge 3D printing in immunosensor design for early cancer detection.用于早期癌症检测的免疫传感器设计中的前沿3D打印技术。
Mikrochim Acta. 2024 Dec 30;192(1):42. doi: 10.1007/s00604-024-06880-6.
3
Point-of-Care Detection of Carcinoembryonic Antigen (CEA) Using a Smartphone-Based, Label-Free Electrochemical Immunosensor with Multilayer CuONPs/CNTs/GO on a Disposable Screen-Printed Electrode.

本文引用的文献

1
Controlling the Self-Assembly of Biomolecules into Functional Nanomaterials through Internal Interactions and External Stimulations: A Review.通过内部相互作用和外部刺激控制生物分子自组装成功能纳米材料:综述
Nanomaterials (Basel). 2019 Feb 18;9(2):285. doi: 10.3390/nano9020285.
2
On-Chip Electrochemical Detection of Cholera Using a Polypyrrole-Functionalized Dendritic Gold Sensor.基于聚吡咯功能化树枝状金传感器的芯片上霍乱电化学检测
ACS Sens. 2019 Mar 22;4(3):654-659. doi: 10.1021/acssensors.8b01484. Epub 2019 Feb 28.
3
Facile Synthesis of CuO@TiO-PtCu Nanocomposites as a Signal Amplification Strategy for the Insulin Detection.
使用基于智能手机的无标记电化学免疫传感器在一次性丝网印刷电极上进行多层CuONPs/CNTs/GO检测癌胚抗原(CEA)的即时检测。
Biosensors (Basel). 2024 Dec 7;14(12):600. doi: 10.3390/bios14120600.
4
Detection of tumor marker CA72-4 with an electrochemical immunosensor based on MnO nanosheets and HNM-AuPtPd nanocomposites.基于 MnO 纳米片和 HNM-AuPtPd 纳米复合材料的电化学免疫传感器检测肿瘤标志物 CA72-4。
Mikrochim Acta. 2024 Apr 4;191(5):239. doi: 10.1007/s00604-024-06266-8.
5
Lab-made disposable screen-printed electrochemical sensors and immunosensors modified with Pd nanoparticles for Parkinson's disease diagnostics.实验室制造的一次性丝网印刷电化学传感器和免疫传感器,经钯纳米粒子修饰,用于帕金森病诊断。
Mikrochim Acta. 2024 Jan 4;191(1):76. doi: 10.1007/s00604-023-06158-3.
6
The Method and Study of Detecting Phenanthrene in Seawater Based on a Carbon Nanotube-Chitosan Oligosaccharide Modified Electrode Immunosensor.基于碳纳米管-壳寡糖修饰电极免疫传感器检测海水中菲的方法与研究。
Molecules. 2023 Jul 27;28(15):5701. doi: 10.3390/molecules28155701.
7
Molecular Biomarkers and Recent Liquid Biopsy Testing Progress: A Review of the Application of Biosensors for the Diagnosis of Gliomas.分子生物标志物与近期液体活检检测进展:生物传感器在脑胶质瘤诊断中应用的综述
Molecules. 2023 Jul 26;28(15):5660. doi: 10.3390/molecules28155660.
8
Novel Sensitive Electrochemical Immunosensor Development for the Selective Detection of HopQ Bacteria Biomarker.新型敏感电化学免疫传感器的开发用于选择性检测霍普氏菌生物标志物
Biosensors (Basel). 2023 May 8;13(5):527. doi: 10.3390/bios13050527.
9
Immunosensors-The Future of Pathogen Real-Time Detection.免疫传感器——病原体实时检测的未来。
Sensors (Basel). 2022 Dec 13;22(24):9757. doi: 10.3390/s22249757.
10
Label-Free Immunosensor Based on Liquid Crystal and Gold Nanoparticles for Cardiac Troponin I Detection.基于液晶和金纳米粒子的无标记免疫传感器用于心肌肌钙蛋白 I 的检测。
Biosensors (Basel). 2022 Dec 2;12(12):1113. doi: 10.3390/bios12121113.
CuO@TiO-PtCu 纳米复合材料的简便合成及其作为胰岛素检测信号放大策略的应用。
ACS Appl Mater Interfaces. 2019 Mar 6;11(9):8945-8953. doi: 10.1021/acsami.9b01779. Epub 2019 Feb 22.
4
A Novel Carbon Quantum Dots Signal Amplification Strategy Coupled with Sandwich Electrochemiluminescence Immunosensor for the Detection of CA15-3 in Human Serum.一种新型碳量子点信号放大策略结合三明治电化学发光免疫传感器用于人血清中 CA15-3 的检测。
ACS Sens. 2019 Feb 22;4(2):504-512. doi: 10.1021/acssensors.8b01607. Epub 2019 Feb 12.
5
Plasma and Nanomaterials: Fabrication and Biomedical Applications.等离子体与纳米材料:制备与生物医学应用
Nanomaterials (Basel). 2019 Jan 14;9(1):98. doi: 10.3390/nano9010098.
6
Label-free immunosensors based on a novel multi-amplification signal strategy of TiO-NGO/Au@Pd hetero-nanostructures.基于 TiO-NGO/Au@Pd 杂化纳米结构新型多信号放大策略的无标记免疫传感器。
Biosens Bioelectron. 2019 Feb 15;127:174-180. doi: 10.1016/j.bios.2018.12.038. Epub 2018 Dec 27.
7
Luminescent nanomaterials for droplet tracking in a microfluidic trapping array.用于微流控捕获阵列中液滴跟踪的发光纳米材料。
Anal Bioanal Chem. 2019 Jan;411(1):157-170. doi: 10.1007/s00216-018-1448-1. Epub 2018 Nov 28.
8
Development and evaluation of serotype-specific recombinase polymerase amplification combined with lateral flow dipstick assays for the diagnosis of foot-and-mouth disease virus serotype A, O and Asia1.用于诊断口蹄疫病毒A、O和亚洲1型的血清型特异性重组酶聚合酶扩增结合侧向流动试纸条检测方法的开发与评估
BMC Vet Res. 2018 Nov 20;14(1):359. doi: 10.1186/s12917-018-1644-4.
9
In Situ Immobilized Sesamol-Quinone/Carbon Nanoblack-Based Electrochemical Redox Platform for Efficient Bioelectrocatalytic and Immunosensor Applications.用于高效生物电催化和免疫传感器应用的原位固定化芝麻酚醌/碳纳米黑基电化学氧化还原平台
ACS Omega. 2018 Sep 30;3(9):10823-10835. doi: 10.1021/acsomega.8b01296. Epub 2018 Sep 7.
10
Molecular characterization of three novel perforins in common carp (Cyprinus carpio L.) and their expression patterns during larvae ontogeny and in response to immune challenges.鲤(Cyprinus carpio L.)中三种新型穿孔素的分子特征及其在幼体个体发育过程中以及对免疫刺激反应时的表达模式。
BMC Vet Res. 2018 Oct 3;14(1):299. doi: 10.1186/s12917-018-1613-y.