Department of Food and Life Science, Pukyong National University, Busan 48513, Korea.
Department of Food Science and Human Nutrition, Chonbuk National University, Jeonju 54896, Korea.
Mar Drugs. 2019 Jun 18;17(6):361. doi: 10.3390/md17060361.
The marine biosphere is a treasure trove of natural bioactive secondary metabolites and the richest source of structurally diverse and unique compounds, such as phlorotannins and halo-compounds, with high therapeutic potential. Eckol is a precursor compound representing the dibenzo-1,4-dioxin class of phlorotannins abundant in the species, which are marine brown algae having a ubiquitous distribution. In search of compounds having biological activity from macro algae during the past three decades, this particular compound has attracted massive attention for its multiple therapeutic properties and health benefits. Although several varieties of marine algae, seaweed, and phlorotannins have already been well scrutinized, eckol deserves a place of its own because of the therapeutic properties it possesses. The relevant information about this particular compound has not yet been collected in one place; therefore, this review focuses on its biological applications, including its potential health benefits and possible applications to restrain diseases leading to good health. The facts compiled in this review could contribute to novel insights into the functions of eckol and potentially enable its use in different uninvestigated fields.
海洋生物圈是天然生物活性次生代谢物的宝库，也是结构多样和独特化合物的最丰富来源，如多酚和卤代化合物，具有很高的治疗潜力。裂环烯醚萜是一种前体化合物，代表了在 物种中丰富的二苯并-1,4-二恶英类多酚， 是一种分布广泛的海洋褐藻。在过去的三十年中，为了从大型藻类中寻找具有生物活性的化合物，这种特殊的化合物因其多种治疗特性和健康益处而引起了广泛关注。尽管已经对几种海洋藻类、海藻和多酚进行了充分的研究，但由于其具有治疗特性，裂环烯醚萜应该占有一席之地。关于这种特殊化合物的相关信息尚未集中在一个地方收集；因此，本综述重点介绍了其在生物应用方面的作用，包括其潜在的健康益处和可能应用于抑制导致健康的疾病。本综述中汇编的事实可能有助于深入了解裂环烯醚萜的功能，并有可能使其在不同的未研究领域得到应用。
