Department of Endocrinology and Metabolism, University of Health Sciences, Keçiören Health Administration and Research Center, Ankara 06100, Turkey.
World J Gastroenterol. 2019 Jun 14;25(22):2699-2705. doi: 10.3748/wjg.v25.i22.2699.
The exocrine structure is significantly affected by diabetes because of endocrine structure-function disorder within the pancreas. Exocrine pancreatic dysfunction (EPD) is the general name of the malabsorption process resulting from inadequate production, release, decreased activation, and/or insufficient degradation of enzymes required for digestion from pancreatic acinar cells. It is important to diagnose patients early and correctly, since there may be both macro- and micro-nutrient deficiency in EPD. In this paper, EPD, the diabetes-EPD relationship, and the predictive, effective factors affecting the emergence of EPD are briefly explained and summarized with contemporary literature and our experienced based on clinical, lab, and radiological findings.
外分泌结构因胰腺内分泌结构功能障碍而受到显著影响。外分泌胰腺功能障碍 (EPD) 是指由于胰腺腺泡细胞产生、释放、激活减少和/或消化所需酶不足而导致的吸收不良过程的总称。早期正确诊断患者非常重要，因为 EPD 可能同时存在宏量和微量营养素缺乏。本文简要解释并总结了 EPD、糖尿病-EPD 关系以及预测、影响 EPD 发生的有效因素，依据的是临床、实验室和影像学发现以及当代文献和我们的经验。
