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用于治疗食管静脉曲张出血的沃伦分流术。

The Warren shunt in treating bleeding esophageal varices.

作者信息

Busuttil R W, Maywood B T, Tompkins R K

出版信息

West J Med. 1979 Apr;130(4):304-8.

Abstract

In patients who have impaired hepatic reserve, the Warren shunt has been proposed as an effective operation because it decompresses the esophageal varices without disturbing portal perfusion of the liver. However, early reports of high operative mortality and technical difficulties have impeded acceptance of the procedure. The operation was done in a series of 17 patients. All patients in whom elective variceal decompression with a patent splenic vein was required and without clinical ascites were candidates for this operation. Follow-up ranged from 2 to 48 months. Six patients had alcoholic cirrhosis, two had primary biliary cirrhosis and seven had postnecrotic cirrhosis; in two the cause of the liver disease was unknown. Five patients were categorized as Child's class A, nine as class B and three as class C. No intraoperative or early postoperative deaths owing to hemorrhage occurred. However, there was one death two weeks postoperatively from pulmonary sepsis and one death five weeks postoperatively due to antigen-positive hepatitis. Two patients died from hepatic failure six weeks and five months after operation, respectively; in the first of these, chronic active hepatitis was diagnosed at the time of operation. In one patient hemorrhage recurred and transfusion was required. Although ascites, which eventually resolved, developed in eight patients after operation, the results in 76 percent of patients have been good without new episodes of hemorrhage or encephalopathy. We conclude that the Warren shunt is a safe and effective elective operation for the treatment of patients in whom hemorrhage from esophageal varices has occurred.

摘要

对于肝储备功能受损的患者,有人提出沃伦分流术是一种有效的手术,因为它能使食管静脉曲张减压,而不会干扰肝脏的门静脉灌注。然而,早期关于手术死亡率高和技术困难的报道阻碍了该手术的推广。对17例患者实施了该手术。所有需要通过通畅的脾静脉进行择期静脉曲张减压且无临床腹水的患者均为此手术的候选对象。随访时间为2至48个月。6例患者为酒精性肝硬化,2例为原发性胆汁性肝硬化,7例为坏死后肝硬化;2例患者的肝病病因不明。5例患者属于Child A级,9例属于B级,3例属于C级。术中及术后早期无因出血导致的死亡。然而,术后两周有1例死于肺部感染,术后五周有1例死于抗原阳性肝炎。2例患者分别在术后六周和五个月死于肝衰竭;其中第一例在手术时被诊断为慢性活动性肝炎。1例患者出血复发,需要输血。尽管8例患者术后出现了腹水,但腹水最终消退,76%的患者情况良好,未出现新的出血或脑病发作。我们得出结论,沃伦分流术对于治疗发生食管静脉曲张出血的患者是一种安全有效的择期手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6727/1238617/09b29d2fdee5/westjmed00248-0016-a.jpg

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