a Instituto Nacional de Salud Pública (INSP), Centro de Investigación Sobre Enfermedades Infecciosas (CISEI), Laboratorio de Resistencia Bacteriana , Cuernavaca , México.
Emerg Microbes Infect. 2019;8(1):973-988. doi: 10.1080/22221751.2019.1634981.
The complex comprises seven related species, including . is a versatile bacterium capable of colonizing different hosts such as plants, humans, insects and animals. Currently, is gaining recognition as a cause of several human infections; nevertheless, its virulence profile is not fully characterized. The clinical significance of infection is hidden by imprecise detection methods that underestimate its real prevalence; however, several methods have been developed to correctly identify this species. Recent studies of carbapenemase-producing and colistin-resistant strains demonstrate a potential reservoir of multidrug-resistant genes. This finding presents an imminent scenario for spreading antimicrobial resistant genes among close relatives and, more concerningly, in clinical and environmental settings. Since was identified as a novel bacterial species, different research groups have contributed findings elucidating this pathogen; however, important details about its epidemiology, pathogenesis and ecology are still missing. This review highlights the most significant aspects of , discussing its different phenotypes, mechanisms of resistance, and virulence traits, as well as the types of infections associated with this pathogen.
该复合体包含七个相关物种，包括 。 是一种多功能细菌，能够定殖于不同的宿主，如植物、人类、昆虫和动物。目前， 被认为是引起几种人类感染的原因；然而，其毒力特征尚未完全确定。由于检测方法不精确，低估了其真正的流行率， 感染的临床意义被隐藏起来；然而，已经开发了几种方法来正确识别该物种。最近对产碳青霉烯酶和多粘菌素耐药菌株的研究表明，该菌可能是多药耐药基因的储库。这一发现预示着在密切相关的细菌之间，更令人担忧的是在临床和环境环境中，传播抗微生物耐药基因的情况迫在眉睫。由于 被鉴定为一种新型细菌，不同的研究小组已经提供了关于该病原体的研究结果；然而，关于其流行病学、发病机制和生态学的重要细节仍然缺失。本综述重点介绍了 的重要方面，讨论了其不同的表型、耐药机制和毒力特征，以及与该病原体相关的感染类型。
