Division of Allergy, Immunology and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine, 1 Children's Place, Campus Box 8116, Saint Louis, MO 63110, USA.
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, 425 S. Euclid Avenue, CB 8052, Saint Louis, MO 63110, USA.
Immunol Allergy Clin North Am. 2019 Aug;39(3):391-401. doi: 10.1016/j.iac.2019.03.007. Epub 2019 May 16.
Respiratory viruses other than rhinovirus or respiratory syncytial virus, including human metapneumovirus, influenza virus, and human bocavirus, are important pathogens in acute wheezing illness and asthma exacerbations in young children. Whether infection with these viruses in early life is associated with recurrent wheezing and/or asthma is not fully investigated, although there are data to suggest children with human metapneumovirus lower respiratory tract infection may have a higher likelihood of subsequent and recurrent wheezing several years after initial infection.
除了鼻病毒或呼吸道合胞病毒以外的呼吸道病毒,包括人偏肺病毒、流感病毒和人博卡病毒,是导致幼儿急性喘息性疾病和哮喘恶化的重要病原体。虽然有数据表明,人偏肺病毒下呼吸道感染的儿童在初次感染后几年内发生后续和反复喘息的可能性更高,但早期感染这些病毒是否与反复喘息和/或哮喘有关尚未得到充分研究。