• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

除了呼吸道合胞病毒和鼻病毒在哮喘发病机制和加重中的作用外:副黏液病毒、博卡病毒和流感病毒的作用。

Beyond Respiratory Syncytial Virus and Rhinovirus in the Pathogenesis and Exacerbation of Asthma: The Role of Metapneumovirus, Bocavirus and Influenza Virus.

机构信息

Division of Allergy, Immunology and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine, 1 Children's Place, Campus Box 8116, Saint Louis, MO 63110, USA.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University School of Medicine, 425 S. Euclid Avenue, CB 8052, Saint Louis, MO 63110, USA.

出版信息

Immunol Allergy Clin North Am. 2019 Aug;39(3):391-401. doi: 10.1016/j.iac.2019.03.007. Epub 2019 May 16.

DOI:10.1016/j.iac.2019.03.007
PMID:31284928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7127190/
Abstract

Respiratory viruses other than rhinovirus or respiratory syncytial virus, including human metapneumovirus, influenza virus, and human bocavirus, are important pathogens in acute wheezing illness and asthma exacerbations in young children. Whether infection with these viruses in early life is associated with recurrent wheezing and/or asthma is not fully investigated, although there are data to suggest children with human metapneumovirus lower respiratory tract infection may have a higher likelihood of subsequent and recurrent wheezing several years after initial infection.

摘要

除了鼻病毒或呼吸道合胞病毒以外的呼吸道病毒,包括人偏肺病毒、流感病毒和人博卡病毒,是导致幼儿急性喘息性疾病和哮喘恶化的重要病原体。虽然有数据表明,人偏肺病毒下呼吸道感染的儿童在初次感染后几年内发生后续和反复喘息的可能性更高,但早期感染这些病毒是否与反复喘息和/或哮喘有关尚未得到充分研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/923d/7127190/0048229ca706/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/923d/7127190/0048229ca706/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/923d/7127190/0048229ca706/gr1_lrg.jpg

相似文献

1
Beyond Respiratory Syncytial Virus and Rhinovirus in the Pathogenesis and Exacerbation of Asthma: The Role of Metapneumovirus, Bocavirus and Influenza Virus.除了呼吸道合胞病毒和鼻病毒在哮喘发病机制和加重中的作用外:副黏液病毒、博卡病毒和流感病毒的作用。
Immunol Allergy Clin North Am. 2019 Aug;39(3):391-401. doi: 10.1016/j.iac.2019.03.007. Epub 2019 May 16.
2
Pediatric Asthma and Viral Infection.小儿哮喘与病毒感染
Arch Bronconeumol. 2016 May;52(5):269-73. doi: 10.1016/j.arbres.2015.11.008. Epub 2016 Jan 4.
3
[New respiratory viruses in children 2 months to 3 years old with recurrent wheeze].2至3岁反复喘息儿童中的新型呼吸道病毒
Arch Argent Pediatr. 2008 Aug;106(4):302-9. doi: 10.1590/S0325-00752008000400005.
4
The first wheezing episode: respiratory virus etiology, atopic characteristics, and illness severity.首次喘息发作:呼吸道病毒病因、特应性特征及疾病严重程度。
Pediatr Allergy Immunol. 2014 Dec;25(8):796-803. doi: 10.1111/pai.12318.
5
Human bocavirus and metapneumovirus in acute wheezing in children-Is there a link with atopy?人博卡病毒和人偏肺病毒与儿童急性喘息——与特应性体质有关联吗?
Clin Respir J. 2020 Dec;14(12):1201-1207. doi: 10.1111/crj.13261. Epub 2020 Sep 7.
6
Detection of viruses identified recently in children with acute wheezing.近期在急性喘息儿童中发现的病毒检测
J Med Virol. 2007 Aug;79(8):1238-43. doi: 10.1002/jmv.20926.
7
Prevalence of rhinovirus in wheezing children: a comparison with respiratory syncytial virus wheezing.喘息儿童中鼻病毒的患病率:与呼吸道合胞病毒喘息的比较。
Braz J Infect Dis. 2016 Mar-Apr;20(2):179-83. doi: 10.1016/j.bjid.2015.12.005. Epub 2016 Feb 7.
8
Prevalence of respiratory viruses in wheezing children not older than 24 months of age.24个月龄及以下喘息儿童呼吸道病毒的流行情况。
Gac Med Mex. 2017 May-Jun;153(3):329-334.
9
Viral Infections and Wheezing in Preschool Children.病毒感染与学龄前儿童喘息
Immunol Allergy Clin North Am. 2022 Nov;42(4):727-741. doi: 10.1016/j.iac.2022.05.004. Epub 2022 Sep 24.
10
Regional, age and respiratory-secretion-specific prevalence of respiratory viruses associated with asthma exacerbation: a literature review.与哮喘加重相关的呼吸道病毒的区域性、年龄和呼吸道分泌物特异性流行情况:文献综述。
Arch Virol. 2018 Apr;163(4):845-853. doi: 10.1007/s00705-017-3700-y. Epub 2018 Jan 11.

引用本文的文献

1
Pre-Existing Allergic Inflammation Alters Both Innate and Adaptive Immune Responses in Mice Co-Infected with Influenza Virus.既往存在的变应性炎症改变了感染流感病毒的小鼠的固有免疫和适应性免疫反应。
Int J Mol Sci. 2025 Apr 8;26(8):3483. doi: 10.3390/ijms26083483.
2
The Association Between Respiratory Viruses and Asthma Exacerbation in Children Visiting Pediatric Emergency Department: A Retrospective Cohort Study.儿童急诊科就诊时呼吸道病毒与哮喘急性加重之间的关联:一项回顾性队列研究。
J Clin Med. 2025 Feb 16;14(4):1311. doi: 10.3390/jcm14041311.
3
Clinical status and cytokine profiles in patients with asthma or chronic obstructive pulmonary disease vaccinated against influenza.

本文引用的文献

1
IL-33 drives influenza-induced asthma exacerbations by halting innate and adaptive antiviral immunity.IL-33 通过阻断先天和适应性抗病毒免疫来驱动流感诱导的哮喘恶化。
J Allergy Clin Immunol. 2019 Apr;143(4):1355-1370.e16. doi: 10.1016/j.jaci.2018.08.051. Epub 2018 Oct 12.
2
Influenza in Asthmatics: For Better or for Worse?哮喘患者的流感:是好是坏?
Front Immunol. 2018 Aug 10;9:1843. doi: 10.3389/fimmu.2018.01843. eCollection 2018.
3
Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices-United States, 2018-19 Influenza Season.
接种流感疫苗的哮喘或慢性阻塞性肺疾病患者的临床状况和细胞因子谱。
PLoS One. 2025 Feb 12;20(2):e0313539. doi: 10.1371/journal.pone.0313539. eCollection 2025.
4
Lung microbiota: implications and interactions in chronic pulmonary diseases.肺部微生物组:慢性肺部疾病的影响和相互作用。
Front Cell Infect Microbiol. 2024 Aug 19;14:1401448. doi: 10.3389/fcimb.2024.1401448. eCollection 2024.
5
Pollen and viruses contribute to spatio-temporal variation in asthma-related emergency department visits.花粉和病毒导致与哮喘相关的急诊科就诊的时空变化。
Environ Res. 2024 Sep 15;257:119346. doi: 10.1016/j.envres.2024.119346. Epub 2024 Jun 3.
6
The role of dendritic cells in respiratory viral infection.树突状细胞在呼吸道病毒感染中的作用。
Eur Respir Rev. 2024 May 29;33(172). doi: 10.1183/16000617.0250-2023. Print 2024 Apr 30.
7
Clinical and epidemiological characteristics of 96 pediatric human metapneumovirus infections in Henan, China after COVID-19 pandemic: a retrospective analysis.中国河南 COVID-19 大流行后 96 例儿童人偏肺病毒感染的临床和流行病学特征:回顾性分析。
Virol J. 2024 Apr 30;21(1):100. doi: 10.1186/s12985-024-02376-0.
8
Suppressed pediatric asthma hospitalizations during the COVID-19 pandemic in Japan, from a national survey.日本全国调查显示,新冠疫情期间小儿哮喘住院率下降。
Clin Transl Allergy. 2024 Jan;14(1):e12330. doi: 10.1002/clt2.12330.
9
Epidemiology and Immunopathogenesis of Virus Associated Asthma Exacerbations.病毒相关性哮喘加重的流行病学与免疫发病机制
J Asthma Allergy. 2023 Sep 26;16:1025-1040. doi: 10.2147/JAA.S277455. eCollection 2023.
10
Moderate-to-severe lower respiratory tract infection in early life is associated with increased risk of polysensitization and atopic dermatitis: Findings from the CHILD Study.儿童早期中重度下呼吸道感染与多重致敏及特应性皮炎风险增加相关:CHILD研究结果
J Allergy Clin Immunol Glob. 2022 Jan 17;1(2):73-79. doi: 10.1016/j.jacig.2021.12.005. eCollection 2022 May.
疫苗预防和控制季节性流感:免疫实践咨询委员会的建议-美国,2018-19 流感季节。
MMWR Recomm Rep. 2018 Aug 24;67(3):1-20. doi: 10.15585/mmwr.rr6703a1.
4
Initial Influenza Virus Replication Can Be Limited in Allergic Asthma Through Rapid Induction of Type III Interferons in Respiratory Epithelium.初始流感病毒复制可通过呼吸道上皮细胞中 III 型干扰素的快速诱导在过敏性哮喘中受到限制。
Front Immunol. 2018 May 17;9:986. doi: 10.3389/fimmu.2018.00986. eCollection 2018.
5
Recurrent wheezing in children following human metapneumovirus infection.儿童感染人偏肺病毒后反复喘息。
J Allergy Clin Immunol. 2018 Jul;142(1):297-301.e2. doi: 10.1016/j.jaci.2018.02.008. Epub 2018 Mar 2.
6
Epidemiological and clinical features of human metapneumovirus in hospitalised paediatric patients with acute respiratory illness: a cross-sectional study in Southern China, from 2013 to 2016.住院急性呼吸道疾病患儿人偏肺病毒的流行病学及临床特征:2013年至2016年中国南方的一项横断面研究
BMJ Open. 2018 Feb 6;8(2):e019308. doi: 10.1136/bmjopen-2017-019308.
7
Regional, age and respiratory-secretion-specific prevalence of respiratory viruses associated with asthma exacerbation: a literature review.与哮喘加重相关的呼吸道病毒的区域性、年龄和呼吸道分泌物特异性流行情况:文献综述。
Arch Virol. 2018 Apr;163(4):845-853. doi: 10.1007/s00705-017-3700-y. Epub 2018 Jan 11.
8
Human metapnuemovirus infections in hospitalized children and comparison with other respiratory viruses. 2005-2014 prospective study.住院儿童的人偏肺病毒感染及其与其他呼吸道病毒的比较。2005 - 2014年前瞻性研究。
PLoS One. 2017 Mar 16;12(3):e0173504. doi: 10.1371/journal.pone.0173504. eCollection 2017.
9
Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus.嗜酸性粒细胞促进感染甲型流感病毒小鼠的抗病毒免疫。
J Immunol. 2017 Apr 15;198(8):3214-3226. doi: 10.4049/jimmunol.1600787. Epub 2017 Mar 10.
10
Human bocavirus: Current knowledge and future challenges.人博卡病毒:当前认知与未来挑战。
World J Gastroenterol. 2016 Oct 21;22(39):8684-8697. doi: 10.3748/wjg.v22.i39.8684.