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深度学习术前预测初次全膝关节置换术的价值指标:人工神经网络模型的建立与验证。

Deep Learning Preoperatively Predicts Value Metrics for Primary Total Knee Arthroplasty: Development and Validation of an Artificial Neural Network Model.

机构信息

Department of Orthopedic Surgery, Cleveland Clinic, Cleveland, OH.

Said Business School, University of Oxford, Oxford, United Kingdom.

出版信息

J Arthroplasty. 2019 Oct;34(10):2220-2227.e1. doi: 10.1016/j.arth.2019.05.034. Epub 2019 Jun 20.

Abstract

BACKGROUND

The objective is to develop and validate an artificial neural network (ANN) that learns and predicts length of stay (LOS), inpatient charges, and discharge disposition before primary total knee arthroplasty (TKA). The secondary objective applied the ANN to propose a risk-based, patient-specific payment model (PSPM) commensurate with case complexity.

METHODS

Using data from 175,042 primary TKAs from the National Inpatient Sample and an institutional database, an ANN was developed to predict LOS, charges, and disposition using 15 preoperative variables. Outcome metrics included accuracy and area under the curve for a receiver operating characteristic curve. Model uncertainty was stratified by All Patient Refined comorbidity indices in establishing a risk-based PSPM.

RESULTS

The dynamic model demonstrated "learning" in the first 30 training rounds with areas under the curve of 74.8%, 82.8%, and 76.1% for LOS, charges, and discharge disposition, respectively. The PSPM demonstrated that as patient comorbidity increased, risk increased by 2.0%, 21.8%, and 82.6% for moderate, major, and severe comorbidities, respectively.

CONCLUSION

Our deep learning model demonstrated "learning" with acceptable validity, reliability, and responsiveness in predicting value metrics, offering the ability to preoperatively plan for TKA episodes of care. This model may be applied to a PSPM proposing tiered reimbursements reflecting case complexity.

摘要

背景

目的是开发和验证一种人工神经网络(ANN),该网络可以在初次全膝关节置换术(TKA)之前学习和预测住院时间(LOS)、住院费用和出院处置。次要目标是将 ANN 应用于提出与病例复杂性相符的基于风险的患者特定支付模型(PSPM)。

方法

使用来自国家住院患者样本和机构数据库的 175042 例初次 TKA 的数据,开发了一种 ANN 来使用 15 个术前变量预测 LOS、费用和处置。结果指标包括接受者操作特征曲线的准确性和曲线下面积。通过对所有患者细化合并症指数进行分层,确定了基于风险的 PSPM 的模型不确定性。

结果

动态模型在最初的 30 次训练回合中表现出“学习”,LOS、费用和出院处置的曲线下面积分别为 74.8%、82.8%和 76.1%。PSPM 表明,随着患者合并症的增加,中度、重度和重度合并症的风险分别增加 2.0%、21.8%和 82.6%。

结论

我们的深度学习模型在预测价值指标方面表现出“学习”,具有可接受的有效性、可靠性和响应能力,为 TKA 护理的术前计划提供了能力。该模型可应用于提出反映病例复杂性的分层报销的 PSPM。

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