Department of Orthopaedic Surgery, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia, USA.
Johns Hopkins Department of Orthopaedic Surgery, Adult Reconstruction Division, John Hopkins Medicine, Baltimore, Maryland, USA.
Bone Joint J. 2021 Aug;103-B(8):1358-1366. doi: 10.1302/0301-620X.103B8.BJJ-2020-1013.R2.
This study used an artificial neural network (ANN) model to determine the most important pre- and perioperative variables to predict same-day discharge in patients undergoing total knee arthroplasty (TKA).
Data for this study were collected from the National Surgery Quality Improvement Program (NSQIP) database from the year 2018. Patients who received a primary, elective, unilateral TKA with a diagnosis of primary osteoarthritis were included. Demographic, preoperative, and intraoperative variables were analyzed. The ANN model was compared to a logistic regression model, which is a conventional machine-learning algorithm. Variables collected from 28,742 patients were analyzed based on their contribution to hospital length of stay.
The predictability of the ANN model, area under the curve (AUC) = 0.801, was similar to the logistic regression model (AUC = 0.796) and identified certain variables as important factors to predict same-day discharge. The ten most important factors favouring same-day discharge in the ANN model include preoperative sodium, preoperative international normalized ratio, BMI, age, anaesthesia type, operating time, dyspnoea status, functional status, race, anaemia status, and chronic obstructive pulmonary disease (COPD). Six of these variables were also found to be significant on logistic regression analysis.
Both ANN modelling and logistic regression analysis revealed clinically important factors in predicting patients who can undergo safely undergo same-day discharge from an outpatient TKA. The ANN model provides a beneficial approach to help determine which perioperative factors can predict same-day discharge as of 2018 perioperative recovery protocols. Cite this article: 2021;103-B(8):1358-1366.
本研究使用人工神经网络(ANN)模型来确定最重要的术前和围手术期变量,以预测接受全膝关节置换术(TKA)的患者的当日出院。
本研究的数据来自 2018 年国家手术质量改进计划(NSQIP)数据库。纳入接受原发性、择期、单侧 TKA 且诊断为原发性骨关节炎的患者。分析了人口统计学、术前和术中变量。将 ANN 模型与逻辑回归模型(一种传统的机器学习算法)进行了比较。根据对住院时间的贡献,分析了来自 28742 名患者的变量。
ANN 模型的可预测性(曲线下面积 [AUC] = 0.801)与逻辑回归模型(AUC = 0.796)相似,并确定了某些变量作为预测当日出院的重要因素。ANN 模型中有利于当日出院的 10 个最重要因素包括术前钠、术前国际标准化比值、BMI、年龄、麻醉类型、手术时间、呼吸困难状态、功能状态、种族、贫血状态和慢性阻塞性肺疾病(COPD)。其中 6 个变量在逻辑回归分析中也具有统计学意义。
ANN 建模和逻辑回归分析都揭示了预测能够安全接受门诊 TKA 当日出院的患者的临床重要因素。ANN 模型提供了一种有益的方法,有助于确定 2018 年围手术期恢复方案中哪些围手术期因素可以预测当日出院。