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哪些干预措施最有效能改善虚弱前期和虚弱老年人的身体机能?一项随机对照试验的系统评价。

What are the most effective interventions to improve physical performance in pre-frail and frail adults? A systematic review of randomised control trials.

机构信息

School of Natural Sciences and Psychology, Liverpool John Moores University, Liverpool, UK.

School of Health Science, University of Surrey, Surrey, GU2 7YH, UK.

出版信息

BMC Geriatr. 2019 Jul 11;19(1):184. doi: 10.1186/s12877-019-1196-x.

Abstract

BACKGROUND

With life expectancy continuing to rise in the United Kingdom there is an increasing public health focus on the maintenance of physical independence among all older adults. Identifying interventions that improve physical outcomes in pre-frail and frail older adults is imperative.

METHODS

A systematic review of the literature 2000 to 2017 following PRISMA guidelines and registered with PROSPERO (no. CRD42016045325).

RESULTS

Ten RCT trials fulfilled selection criteria and quality appraisal. The study quality was moderate to good. Interventions included physical activity; nutrition, physical activity combined with nutrition. Interventions that incorporated one or more physical activity components significantly improved physical outcomes in pre-frail and/or frail older adults.

CONCLUSIONS

Physical activity interventions are key to maintaining independence in pre-frail and frail older adults. A lack of consensus regarding the definition of frailty, and an absence of core measures to assess this means any attempt to create an optimal intervention will be impeded. This absence may ultimately impact on the ability of older and frail adults to live well and for longer in the community.

摘要

背景

随着英国预期寿命的持续延长,公众越来越关注所有老年人保持身体独立。确定可以改善虚弱和脆弱老年人身体状况的干预措施至关重要。

方法

根据 PRISMA 指南对 2000 年至 2017 年的文献进行系统综述,并在 PROSPERO 上进行了注册(编号 CRD42016045325)。

结果

十项 RCT 试验符合选择标准和质量评估。研究质量为中等至良好。干预措施包括体育活动;营养,体育活动与营养相结合。纳入一个或多个体育活动组成部分的干预措施可显著改善虚弱和/或脆弱老年人的身体状况。

结论

体育活动干预是维持虚弱和脆弱老年人独立性的关键。对虚弱的定义缺乏共识,缺乏评估这一定义的核心措施,这意味着任何试图制定最佳干预措施的尝试都将受到阻碍。这种缺失最终可能会影响老年人和虚弱成年人在社区中生活得更好和更久的能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be46/6622112/9c9fb8a5838a/12877_2019_1196_Fig1_HTML.jpg

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