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声表面波-PDMS 流控建模:不同 PDMS 域描述对物理场和颗粒运动的影响。

Modelling of SAW-PDMS acoustofluidics: physical fields and particle motions influenced by different descriptions of the PDMS domain.

机构信息

Key Laboratory of Modern Acoustics (MOE), Department of Physics, Collaborative Innovation Center of Advanced Microstructure, Nanjing University, Nanjing 210093, China.

出版信息

Lab Chip. 2019 Aug 21;19(16):2728-2740. doi: 10.1039/c9lc00431a. Epub 2019 Jul 11.

DOI:10.1039/c9lc00431a
PMID:31292597
Abstract

In modelling acoustofluidic chips actuated by surface acoustic waves (SAWs) and using polydimethylsilane (PDMS) as a channel material, reduced models are often adopted to describe the acoustic behaviors of PDMS. Here, based on a standing SAW (SSAW) acoustophoresis chip, we compared three different descriptions of a PDMS chamber and looked into in-chamber physical fields and ensuing particle motion processes through finite element (FE) simulations. Specifically, the PDMS domain was considered as an elastic solid material, a non-flow fluid, and a lossy wall, respectively. The major findings include: (a) the shear waves that propagated in a solid PDMS wall did not influence the in-chamber pressure and ARF fields severely, but induced an observable difference in the acoustic streaming (AS) patterns, and distinctly changed the trajectories of polystyrene particles, especially those whose radii were below 1.5 μm; and (b) the equivalent damping coefficients were linearly dependent on the SAW frequency, characterized by a fixed loss per wavelength, indicating the wave leakage at the interface being the main source of the transmission loss of SAWs. Meanwhile, the acoustic radiation force (ARF) can be overestimated when describing PDMS as a lossy wall, especially at the bottom corners of the chamber, which could cause inaccurate predictions of the motion of big particles. Based on the damping mechanism, a rough protocol is provided for scaling of pressure fields between different models. Some suggestions for device designs and operations are also given based on the obtained findings.

摘要

在对表面声波(SAW)驱动的声流控芯片建模并使用聚二甲基硅氧烷(PDMS)作为通道材料时,通常采用简化模型来描述 PDMS 的声学行为。在这里,我们基于驻波 SAW(SSAW)声泳芯片,比较了 PDMS 腔室的三种不同描述,并通过有限元(FE)模拟研究了腔内物理场和随后的颗粒运动过程。具体来说,PDMS 域分别被视为弹性固体材料、无流动流体和有耗壁。主要发现包括:(a)在固体 PDMS 壁中传播的剪切波不会严重影响腔内压力和 ARF 场,但会引起声流(AS)模式的可观察差异,并明显改变聚苯乙烯颗粒的轨迹,特别是那些半径小于 1.5μm 的颗粒;(b)等效阻尼系数与 SAW 频率呈线性关系,每波长具有固定的损耗,表明界面处的波泄漏是 SAW 传输损耗的主要来源。同时,当将 PDMS 描述为有耗壁时,声辐射力(ARF)可能会被高估,特别是在腔室的底部角落,这可能导致对大颗粒运动的不准确预测。基于阻尼机制,提供了不同模型之间压力场缩放的大致方案。根据获得的结果,还给出了一些器件设计和操作的建议。

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