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越南发现的一种新型副黏液病毒(汉坦病毒科)——达孔榕病毒,宿主为越南斯氏菊头蝠(Aselliscus stoliczkanus)。

Đakrông virus, a novel mobatvirus (Hantaviridae) harbored by the Stoliczka's Asian trident bat (Aselliscus stoliczkanus) in Vietnam.

机构信息

Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan.

Tokyo University of Science, Tokyo, 162-8601, Japan.

出版信息

Sci Rep. 2019 Jul 15;9(1):10239. doi: 10.1038/s41598-019-46697-5.

Abstract

The recent discovery of genetically distinct shrew- and mole-borne viruses belonging to the newly defined family Hantaviridae (order Bunyavirales) has spurred an extended search for hantaviruses in RNAlater®-preserved lung tissues from 215 bats (order Chiroptera) representing five families (Hipposideridae, Megadermatidae, Pteropodidae, Rhinolophidae and Vespertilionidae), collected in Vietnam during 2012 to 2014. A newly identified hantavirus, designated Đakrông virus (DKGV), was detected in one of two Stoliczka's Asian trident bats (Aselliscus stoliczkanus), from Đakrông Nature Reserve in Quảng Trị Province. Using maximum-likelihood and Bayesian methods, phylogenetic trees based on the full-length S, M and L segments showed that DKGV occupied a basal position with other mobatviruses, suggesting that primordial hantaviruses may have been hosted by ancestral bats.

摘要

最近发现了属于新定义的汉坦病毒科(布尼亚病毒目)的具有遗传差异的鼩鼱和鼹鼠传播病毒,这促使人们在越南从 2012 年到 2014 年采集的代表五个科(蹄蝠科、食果蝠科、菊头蝠科、菊头蝠科和蝙蝠科)的 215 只蝙蝠(翼手目)的 RNAlater®保存的肺组织中,对汉坦病毒进行了广泛搜索。在广治省的达克荣自然保护区,从两种亚洲三叉戟蝙蝠(Aselliscus stoliczkanus)中发现了一种新鉴定的汉坦病毒,命名为达克荣病毒(DKGV)。使用最大似然法和贝叶斯方法,基于全长 S、M 和 L 片段构建的系统发育树显示,DKGV 与其他移行病毒占据了一个基础位置,这表明原始汉坦病毒可能由祖先蝙蝠携带。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/529d/6629698/3f323b3ba6b6/41598_2019_46697_Fig1_HTML.jpg

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