Emerg Infect Dis. 2019 Aug;25(8):1594-1596. doi: 10.3201/eid2508.181489.
We implemented subgenomic and whole-genome sequencing to support the investigation of a large hepatitis A virus outbreak among persons experiencing homelessness, users of illicit drugs, or both in California, USA, during 2017-2018. Genotyping data helped confirm case-patients, track chains of transmission, and monitor the effectiveness of public health control measures.
我们实施了亚基因组和全基因组测序,以支持在美国加利福尼亚州 2017-2018 年期间针对无家可归者、非法药物使用者或两者兼有的大量甲型肝炎病毒爆发进行的调查。基因分型数据有助于确认病例患者,追踪传播链,并监测公共卫生控制措施的效果。