Baggio G, Pagnan A, Muraca M, Martini S, Opportuno A, Bonanome A, Ambrosio G B, Ferrari S, Guarini P, Piccolo D
Institute of Internal Medicine, University of Padua, Italy.
Am J Clin Nutr. 1988 Jun;47(6):960-4. doi: 10.1093/ajcn/47.6.960.
The effect of diet enriched with a monounsaturated fatty acid (olive oil) on serum lipoproteins, biliary cholesterol saturation index, and gallbladder motility compared with a standard low-fat diet was evaluated in 11 young volunteers admitted to a metabolic ward. A significant decrease of mean total cholesterol (-9.5%), total apo B (-7.4%), LDL cholesterol (-12.2%), and total triglycerides (-25.5%) was observed after the olive-oil-enriched diet. Total HDL- and HDL-subfractions-cholesterol levels as well as serum apo A-I mean levels remained unchanged. Cholesterol saturation index of the bile and fasting and after-meal gallbladder volumes were unaffected by the enriched diet as compared with the low-fat diet. Olive oil may be a natural fat that can be used for the control of plasma and LDL cholesterol as a valid alternative to polyunsaturated fatty acids.
在一所代谢病房收治的11名年轻志愿者中，评估了富含单不饱和脂肪酸（橄榄油）的饮食与标准低脂饮食相比，对血清脂蛋白、胆汁胆固醇饱和指数和胆囊运动的影响。富含橄榄油的饮食后，平均总胆固醇（-9.5%）、总载脂蛋白B（-7.4%）、低密度脂蛋白胆固醇（-12.2%）和总甘油三酯（-25.5%）显著降低。总高密度脂蛋白和高密度脂蛋白亚组分胆固醇水平以及血清载脂蛋白A-I平均水平保持不变。与低脂饮食相比，富含橄榄油的饮食对胆汁胆固醇饱和指数以及空腹和餐后胆囊体积没有影响。橄榄油可能是一种天然脂肪，可作为多不饱和脂肪酸的有效替代品用于控制血浆和低密度脂蛋白胆固醇。
