Algazinа T, Touir G, Pshembayevа S, Jetpisbayeva Z, Batpenova G
NJSC «Astana Medical University», Nur-Sultan, Kazakhstan.
Georgian Med News. 2019 May(290):96-100.
The article discusses the role of vitamin D in the development of skin pathology - in particular, psoriasis and acne. In some publications the results of vitamin D sufficiency in patients with these diseases are cited, but there is still insufficient information to draw definitive conclusions about the role of vitamin D in their development. The aim of the study was to assess the role of vitamin D in psoriasis and acne development. The case-control study involved 66 people, including 20 patients with psoriasis (group 1), 20 with acne (group 2) and 26 healthy individuals (control group). All participants in the study were determined the level of plasma vitamin 25 (OH)D; in patients with psoriasis PASI index to determine the severity of the disease was calculated. Vitamin 25(OH)D deficiency was detected in a significant majority of patients with skin diseases, and its average plasma level in each group was significantly lower than in the control group. There was a correlation between vitamin 25(OH)D deficiency and psoriasis severity. In patients with psoriasis and acne, vitamin D preparations should be included in the treatment complex to increase the effectiveness of therapy.
本文讨论了维生素D在皮肤病理学发展中的作用——特别是在银屑病和痤疮方面。在一些出版物中引用了这些疾病患者维生素D充足的结果，但关于维生素D在其发展中的作用仍缺乏足够信息来得出明确结论。该研究的目的是评估维生素D在银屑病和痤疮发展中的作用。这项病例对照研究涉及66人，包括20名银屑病患者（第1组）、20名痤疮患者（第2组）和26名健康个体（对照组）。研究中的所有参与者都测定了血浆维生素25(OH)D水平；计算了银屑病患者的PASI指数以确定疾病的严重程度。在绝大多数皮肤病患者中检测到维生素25(OH)D缺乏，且每组的平均血浆水平均显著低于对照组。维生素25(OH)D缺乏与银屑病严重程度之间存在相关性。对于银屑病和痤疮患者，治疗方案中应包括维生素D制剂以提高治疗效果。
