Brown School of Social Work, Washington University in St. Louis, St. Louis, MO, USA.
Regional Alliance for Sustainable Development, Kigali, Rwanda.
Glob Heart. 2019 Jun;14(2):135-141. doi: 10.1016/j.gheart.2019.06.001.
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality worldwide and in low- and middle-income countries, and hypertension (HTN) is a major risk factor for CVD. Although effective evidence-based interventions for control of HTN in high-income countries exist, implementation of these in low- and middle-income countries has been challenging due to limited capacity and infrastructure for late-phase translational research. In Rwanda, the 2015 STEPS NCD (STEPwise Approach to Surveillance of Noncommunicable Diseases) risk survey reported an overall prevalence of HTN of 15% (95% confidence interval [CI]: 13.8 to 16.3) for those ages 15 to 64 years; prevalence increased with increasing age to 39% (95% CI: 35.7 to 43.1) for those ages 55 to 64 years; CVD was the third most common cause of mortality (7%). Suboptimal infrastructure and capacity in Rwanda hinders research and community knowledge for HTN control.
To address the issue of suboptimal capacity to implement evidence-based interventions in HTN, this project was designed with the following objectives: 1) to develop a regional needs assessment of infrastructure for dissemination and implementation (D & I) strategies for HTN-CVD control; 2) to develop HTN-CVD research capacity through creation of countrywide resources such as core research facilities and training in the fields of HTN-CVD, D & I, and biostatistics; and 3) to engage and train multiple stakeholders in D & I and HTN-CVD evidence-based interventions.
A weeklong training program in HTN-CVD, biostatistics, and D & I was conducted in Rwanda in August 2018, and pre- and post-D & I training competency questionnaires were administered.
Questionnaire results show a statistically significant increase in D & I knowledge and skills as a result of training (full scale pre- to post-test scores: 2.12 ± 0.78 vs. 3.94 ± 0.42; p < 0.0001).
Using principles of community engagement and train-the-trainer methods, we will continue to adapt guidelines and treatments for HTN-CVD developed in high-income countries to the context of Rwanda with the goal of establishing a sustainable platform to address the burden of disease from HTN-CVD.
心血管疾病(CVD)是全球和中低收入国家发病率和死亡率的主要原因,高血压(HTN)是 CVD 的主要危险因素。尽管在高收入国家存在有效的基于证据的 HTN 控制干预措施,但由于缺乏后期转化研究的能力和基础设施,这些措施在中低收入国家的实施具有挑战性。在卢旺达,2015 年 STEPS NCD(逐步方法监测非传染性疾病)风险调查报告称,15 至 64 岁人群的 HTN 总患病率为 15%(95%置信区间[CI]:13.8%至 16.3%);患病率随年龄增长而增加,55 至 64 岁人群的患病率为 39%(95%CI:35.7%至 43.1%);CVD 是第三大常见死因(7%)。卢旺达基础设施和能力不足阻碍了 HTN 控制的研究和社区知识普及。
为了解决实施 HTN 循证干预措施能力不足的问题,本项目旨在实现以下目标:1)评估区域传播和实施(D & I)策略的基础设施,以进行 HTN-CVD 控制;2)通过建立全国性资源,如核心研究设施和 HTN-CVD、D & I 和生物统计学领域的培训,发展 HTN-CVD 研究能力;3)使多方利益相关者参与 D & I 和 HTN-CVD 循证干预措施。
2018 年 8 月在卢旺达进行了为期一周的 HTN-CVD、生物统计学和 D & I 培训计划,并在培训前后进行了 D & I 培训能力问卷。
问卷结果显示,培训后 D & I 知识和技能有了显著提高(全量表测试前到后得分:2.12±0.78 与 3.94±0.42;p<0.0001)。
我们将继续使用社区参与原则和培训师方法,将在高收入国家制定的 HTN-CVD 指南和治疗方法改编为卢旺达的情况,旨在建立一个可持续的平台,以解决 HTN-CVD 带来的疾病负担。