Singh Rajpal, Chufal Kundan Singh, Pahuja Anjali K, Suresh Tamilarasu, Chowdhary Rahul Lal, Ahmad Irfan
Radiation Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, Delhi, India.
BMJ Case Rep. 2019 Jul 18;12(7):e227036. doi: 10.1136/bcr-2018-227036.
A 28-year-old premenopausal woman presented with a painful rapidly growing mass in her right breast and was evaluated with a core needle biopsy, which was suggestive of poorly differentiated carcinoma. Immunohistochemical evaluation revealed primary angiosarcoma of breast. Whole body flouro-deoxyglucose positron emission tomography CT showed few metabolically active soft tissue lesions in upper inner quadrant of right breast. The patient underwent breast conservation surgery and in view of positive surgical margins, received adjuvant radiation therapy. Post-treatment completion, the patient has been disease free for 6 months. Primary angiosarcoma of the breast is a rare malignancy which is best managed with a surgery as first approach, with due importance being given to the patient's perspective on their disease and choices for adjuvant treatment. Decisions in addition to adjuvant radiotherapy need to be made in the multidisciplinary clinic, due to paucity of data.
一名28岁的绝经前女性因右乳出现疼痛性快速生长的肿块前来就诊，接受了粗针活检评估，结果提示为低分化癌。免疫组化评估显示为乳腺原发性血管肉瘤。全身氟脱氧葡萄糖正电子发射断层扫描CT显示右乳上内象限有少数代谢活跃的软组织病变。患者接受了保乳手术，鉴于手术切缘阳性，接受了辅助放疗。治疗结束后，患者已无病生存6个月。乳腺原发性血管肉瘤是一种罕见的恶性肿瘤，最佳治疗方法是以手术作为首选，同时要充分重视患者对自身疾病的看法以及辅助治疗的选择。由于数据有限，除辅助放疗外的其他决策需要在多学科门诊做出。
