Department of Sociology and Woodrow Wilson School of Public and International Affairs, Princeton University, Princeton, NJ, USA.
Department of Sexual and Reproductive Health, National Medical Research Institute, Mwanza, Tanzania.
J Int AIDS Soc. 2019 Jul;22 Suppl 4(Suppl Suppl 4):e25302. doi: 10.1002/jia2.25302.
Significant progress has been made in the African HIV pandemic; however, the pace of incidence decline has slowed or stalled in many East and Southern African countries, especially among young women. This stall is worrying because many countries have burgeoning youth populations. There is an important window of opportunity to halt the epidemic as well as the potential for millions more infections if primary prevention efforts are not strengthened.
Many hyper-endemic settings have been exposed to numerous interventions; however, HIV incidence among young women has remained high. In this paper, we characterize the intervention context and examine how it can be strategically utilized to maximize HIV prevention interventions among young women. We begin by examining how contextual dynamics drive HIV risk. We illustrate how epidemiological contexts, gendered normative and economic contexts, and environmental contexts work synergistically to make young women especially vulnerable to HIV infection. We then examine how these contexts can undermine HIV prevention interventions. Finally, we discuss the importance of fully mapping out the intervention context to enhance the effectiveness of HIV prevention interventions.
Understanding an intervention context, and how its features work together to amplify young women's risk in hyper-endemic settings can contribute to sustained momentum in reducing HIV incidence among young women and help to limit the reach of the HIV pandemic into new generations of Africans.
在非洲的艾滋病大流行中已经取得了显著进展;然而,在许多东非和南非国家,尤其是在年轻女性中,发病率下降的速度已经放缓或停滞不前。这种停滞令人担忧,因为许多国家的青年人口正在迅速增长。如果不加强初级预防工作,就有一个重要的机会之窗来阻止疫情的蔓延,以及避免数百万人感染艾滋病的潜在风险。
许多高度流行的地区已经接触到了许多干预措施;然而,年轻女性中的艾滋病发病率仍然很高。在本文中,我们描述了干预背景,并研究了如何战略性地利用它来最大限度地提高针对年轻女性的艾滋病预防干预措施。我们首先研究了背景动态如何驱动艾滋病风险。我们说明了流行病学背景、性别规范和经济背景以及环境背景如何协同作用,使年轻女性特别容易感染艾滋病。然后,我们研究了这些背景如何破坏艾滋病预防干预措施。最后,我们讨论了全面描绘干预背景以提高艾滋病预防干预措施的有效性的重要性。
了解干预背景,以及其特征如何协同作用,放大了高度流行地区年轻女性的风险,可以为持续减少年轻女性的艾滋病发病率做出贡献,并有助于限制艾滋病在非洲新一代人中的传播。