School of Psychology and Counselling, and Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia.
School of Psychiatry, University of New South Wales, Sydney, New South Wales, Australia.
Br J Clin Psychol. 2020 Mar;59(1):22-38. doi: 10.1111/bjc.12230. Epub 2019 Jul 22.
Childhood psychotic-like experiences (PLEs) increase risk for concurrent and future psychiatric disorders but are common in the population. Strategies are needed to identify vulnerable individuals who may benefit from monitoring or targeted intervention. This study aimed to delineate profiles of childhood PLEs that might be differentially associated with other psychopathologies, and multiple psychopathology.
Cross-sectional, online self-report survey.
Participants were 27,000 Australian children from a population cohort (13,416 girls; mean age 11.91 years) who completed an online self-report questionnaire assessing PLEs (hallucinations and delusions) and Emotional, Peer Relationship, Conduct, and Hyperactivity-Inattention psychopathology. Latent class analysis differentiated classes of children showing different patterns of PLE responses, and multinomial logistic regression determined the association between the PLE classes and the various psychopathologies, adjusted for demographic covariates and the other psychopathologies.
Five latent profiles of PLE responses were characterized as follows: None (27.4% of children), Minor (29.7%), Moderate (11.8%), Hallucinatory (21.0%), and Strong (10.2%). These classes showed distinct associations with other psychopathologies (odds ratios between 1.27 and 4.58), and dose-response relationships indicated increasing likelihood of multiple psychopathology for the Hallucinatory and Strong classes (odds ratio = 21.87 for ≥3 psychopathologies in the Strong class).
Tailored interventions that address the particular needs of these different classes of individuals may be warranted.
Children aged 11-12 years who report psychotic-like experiences (PLEs) can be classified into five different PLE profiles based on self-reported questionnaire responses, which may reflect different pathological processes. These PLE profiles show different patterns and magnitudes of increased risk for other types of psychopathology, and multiple psychopathology, suggesting that they present different treatment needs. Cross-sectional investigation of the associations between PLE profiles and other psychopathologies limits any conclusions as to the causal direction of these relationships. Multi-informant reports of psychopathology were unavailable.
儿童类精神病体验（PLE）会增加同时发生和未来精神障碍的风险，但在人群中很常见。需要采取策略来识别可能受益于监测或有针对性干预的脆弱个体。本研究旨在描绘可能与其他精神病理学和多种精神病理学有不同关联的儿童 PLE 特征。
横断面、在线自我报告调查。
参与者是来自人群队列的 27000 名澳大利亚儿童（13416 名女孩；平均年龄 11.91 岁），他们完成了一项在线自我报告问卷，评估 PLE（幻觉和妄想）以及情绪、同伴关系、行为和多动-注意力不集中的精神病理学。潜在类别分析区分了表现出不同 PLE 反应模式的儿童群体，多变量逻辑回归确定了 PLE 群体与各种精神病理学之间的关联，调整了人口统计学协变量和其他精神病理学。
PLE 反应的五个潜在特征如下：无（27.4%的儿童）、轻微（29.7%）、中度（11.8%）、幻觉（21.0%）和强烈（10.2%）。这些群体与其他精神病理学有明显的关联（比值比在 1.27 到 4.58 之间），并且剂量反应关系表明幻觉和强烈群体的多种精神病理学的可能性增加（强烈群体中≥3 种精神病理学的比值比为 21.87）。
可能需要针对这些不同个体群体的特定需求的量身定制的干预措施。
11-12 岁报告类精神病体验（PLE）的儿童可以根据自我报告问卷的反应分为五个不同的 PLE 特征，这可能反映了不同的病理过程。这些 PLE 特征显示出不同的模式和程度的增加风险，与其他类型的精神病理学和多种精神病理学相关，表明它们有不同的治疗需求。PLE 特征与其他精神病理学之间的横断面关联研究限制了对这些关系因果方向的任何结论。无法获得多信息源的精神病理学报告。
