Generation of Indoles with Agrochemical Significance through Biotransformation by .

Six new (-) and two known ( and ) indole alkaloids were produced by the marine fish-derived fungus 1C51 through biotransformation. The structures of these alkaloids were elucidated by a combination of MS, NMR, and X-ray crystallography analyses. Chaetoindolone A () was shown to inhibit the growth of the rice-pathogenic bacteria pv. () both in vitro and in vivo. Chaetogline A () was found to be fungicidal against , a pathogen causing rape sclerotinia rot. Collectively, this work provides access to new indole alkaloids with potential agrochemical significance.