Department of Biochemistry, Microbiology and Biotechnology, Yerevan State University, Yerevan 0025, Armenia.
Curr Pharm Des. 2019;25(16):1861-1865. doi: 10.2174/1381612825666190716112510.
Overcoming the antibiotic resistance is nowadays a challenge. There is still no clear strategy to combat this problem. Therefore, the urgent need to find new sources of antibacterial agents exists. According to some literature, substances of plant origin are able to overcome bacterial resistance against antibiotics. Alkanna species plants are among the valuable producers of these metabolites. But there is a problem of obtaining the standardized product. So, this review is focused on the discussion of the possibilities of biotechnological production of antimicrobial agents from Alkanna genus species against some microorganisms including antibiotic resistant bacterial strains.
克服抗生素耐药性是当今的一项挑战。目前仍没有明确的策略来解决这个问题。因此，迫切需要寻找新的抗菌剂来源。根据一些文献，植物来源的物质能够克服细菌对抗生素的耐药性。紫菀属植物是这些代谢物的有价值的生产者之一。但是，存在获得标准化产品的问题。因此，本综述重点讨论了利用生物技术生产抗微生物剂的可能性，这些抗微生物剂来自 Alkanna 属的一些物种，针对包括抗生素耐药菌株在内的一些微生物。
