Barman Bhupen, Devi L Purnima, Thakur Binod Kumar, Raphael Vandana
Department of General Medicine, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India.
Department of Radiotherapy and Oncology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India.
Indian Dermatol Online J. 2019 Jul-Aug;10(4):453-455. doi: 10.4103/idoj.IDOJ_427_18.
Tripe palms is an unusual cutaneous paraneoplastic syndrome characterized by a curious rugose thickening of the palms with an accentuation of the normal dermatoglyphic ridges and sulci. Tripe palms alone or in combination with acanthosis nigricans is strongly associated with internal malignancy, especially carcinomas of the gastrointestinal tract and lung. Any patient with tripe palms must have a complete cancer workup, as in many of the cases it often precedes the malignancy by many months. We report a rare case of tripe palms with acanthosis nigricans in a 50-year-old man with advanced pancreatic adenocarcinoma. Although relatively rare, an early diagnosis is very important to find out underlying malignancy and to improve the prognosis related to the neoplasia.
掌跖角化瘤是一种不寻常的皮肤副肿瘤综合征，其特征为手掌出现奇特的皱纹样增厚，正常的皮纹嵴和沟加深。单独的掌跖角化瘤或与黑棘皮病合并出现，都与体内恶性肿瘤密切相关，尤其是胃肠道和肺部的癌症。任何患有掌跖角化瘤的患者都必须进行全面的癌症检查，因为在许多病例中，它往往比恶性肿瘤早出现数月。我们报告了一例50岁晚期胰腺腺癌男性患者出现掌跖角化瘤合并黑棘皮病的罕见病例。尽管相对罕见，但早期诊断对于发现潜在的恶性肿瘤以及改善与肿瘤相关的预后非常重要。
