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胰腺疾病的皮肤表现。

Skin manifestations of pancreatic diseases.

作者信息

Kunovsky Lumir, Dite Petr, Brezinova Eva, Sedlakova Libuse, Trna Jan, Jabandziev Petr

机构信息

Department of Surgery, University Hospital Brno, Czech Republic.

Faculty of Medicine, Masaryk University, Brno, Czech Republic.

出版信息

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022 Dec;166(4):353-358. doi: 10.5507/bp.2022.035. Epub 2022 Jul 22.

DOI:10.5507/bp.2022.035
PMID:35938387
Abstract

Although symptoms of pancreatic diseases such as pancreatitis, acute and chronic and, carcinoma of the pancreas are mainly gastrointestinal in nature, the extra-pancreatic symptoms are also important. These include skin symptoms, such as pancreatic panniculitis, acanthosis nigricans, livedo reticularis, necrolytic migratory erythema, cutaneous signs of hemorrhage, as in persons with severe acute pancreatitis, or the finding of cutaneous metastases of pancreatic carcinoma, which may be a sign of advanced disease. The pancreas is therefore one of those organs for which diagnosis and therapy are often multidisciplinary. In this review article, we summarize current knowledge of the possible skin manifestations of pancreatic disorders.

摘要

尽管胰腺炎(急性和慢性)、胰腺癌等胰腺疾病的症状本质上主要是胃肠道症状,但胰腺外症状也很重要。这些包括皮肤症状,如胰腺性脂膜炎、黑棘皮病、网状青斑、坏死松解性游走性红斑、严重急性胰腺炎患者出现的皮肤出血体征,或胰腺癌皮肤转移的表现,这可能是疾病晚期的迹象。因此,胰腺是诊断和治疗通常需要多学科参与的器官之一。在这篇综述文章中,我们总结了关于胰腺疾病可能出现的皮肤表现的现有知识。

相似文献

1
Skin manifestations of pancreatic diseases.胰腺疾病的皮肤表现。
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2022 Dec;166(4):353-358. doi: 10.5507/bp.2022.035. Epub 2022 Jul 22.
2
Cutaneous Manifestations in Pancreatic Diseases-A Review.胰腺疾病的皮肤表现——综述
J Clin Med. 2020 Aug 12;9(8):2611. doi: 10.3390/jcm9082611.
3
Pancreatic carcinoma presented with panniculitis and polyarthritis: A rare case.胰腺腺癌伴脂膜炎和多发性关节炎:一例罕见病例。
J Cancer Res Ther. 2021 Dec;17(7):1751-1754. doi: 10.4103/jcrt.jcrt_2386_21.
4
Pancreatic panniculitis.胰腺性脂膜炎
J Am Acad Dermatol. 1995 Sep;33(3):413-7. doi: 10.1016/0190-9622(95)91385-8.
5
Cutaneous signs of internal malignancies.内部恶性肿瘤的皮肤表现。
J Surg Oncol. 1983 May;23(1):1-4. doi: 10.1002/jso.2930230102.
6
Pancreatic panniculitis.胰腺性脂膜炎。
G Ital Dermatol Venereol. 2013 Aug;148(4):419-25.
7
[Pancreatic panniculitis with intraductal carcinoid tumor of the pancreas divisum].[胰腺分裂伴胰腺导管内类癌瘤的胰腺脂肪坏死]
Ann Dermatol Venereol. 2004 May;131(5):466-9. doi: 10.1016/s0151-9638(04)93641-1.
8
Cutaneous manifestations of pancreatic diseases.
Cutis. 1978 Jun;21(6):763-8.
9
Painful lower limb nodules as first symptom of resectable pancreatic acinar cell cancer: a case report.以下肢疼痛性结节为首发症状的可切除胰腺腺泡细胞癌 1 例报告
J Med Case Rep. 2022 Oct 5;16(1):356. doi: 10.1186/s13256-022-03595-1.
10
Acinar cell carcinoma of the pancreas associated with subcutaneous panniculitis.胰腺腺泡细胞癌伴皮下脂膜炎
JOP. 2011 May 6;12(3):292-6.

引用本文的文献

1
Skin as a Reflection of Gut Health: An Overview of Dermatological Manifestations in Primary Neoplastic and Autoimmune Gastrointestinal Disorders.皮肤作为肠道健康的反映:原发性肿瘤性和自身免疫性胃肠疾病的皮肤表现概述
Cureus. 2024 Oct 12;16(10):e71313. doi: 10.7759/cureus.71313. eCollection 2024 Oct.
2
Extra-pancreatic manifestations reported in association with pancreatitis; an international survey report.与胰腺炎相关的胰腺外表现:国际调查研究报告。
PLoS One. 2023 Jul 11;18(7):e0288337. doi: 10.1371/journal.pone.0288337. eCollection 2023.

本文引用的文献

1
Cutaneous Manifestations in Pancreatic Diseases-A Review.胰腺疾病的皮肤表现——综述
J Clin Med. 2020 Aug 12;9(8):2611. doi: 10.3390/jcm9082611.
2
Idiopathic extensive acanthosis nigricans with a variant of the epidermal growth factor receptor.伴有表皮生长因子受体变异型的特发性泛发性黑棘皮病
JAAD Case Rep. 2020 Jan 16;6(2):79-82. doi: 10.1016/j.jdcr.2019.10.023. eCollection 2020 Feb.
3
Tripe Palms and Acanthosis Nigricans: A Clue for Diagnosis of Advanced Pancreatic Adenocarcinoma.掌跖角化症与黑棘皮病:诊断晚期胰腺腺癌的线索
Indian Dermatol Online J. 2019 Jul-Aug;10(4):453-455. doi: 10.4103/idoj.IDOJ_427_18.
4
New insights into acute pancreatitis.急性胰腺炎的新见解。
Nat Rev Gastroenterol Hepatol. 2019 Aug;16(8):479-496. doi: 10.1038/s41575-019-0158-2.
5
Pancreatic panniculitis: A case series from a tertiary university hospital in Spain.胰腺性脂膜炎:来自西班牙一所三级大学医院的病例系列
Australas J Dermatol. 2018 Nov;59(4):e269-e272. doi: 10.1111/ajd.12842. Epub 2018 May 9.
6
Panniculitis, pancreatitis, and polyarthritis: a rare clinical syndrome.脂膜炎、胰腺炎和多关节炎:一种罕见的临床综合征。
Cutis. 2018 Jan;101(1):E34-E37.
7
Glucagonoma and the glucagonoma syndrome.胰高血糖素瘤与胰高血糖素瘤综合征。
Oncol Lett. 2018 Mar;15(3):2749-2755. doi: 10.3892/ol.2017.7703. Epub 2017 Dec 28.
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Another cutaneous sign of acute pancreatitis.急性胰腺炎的另一种皮肤表现。
Indian J Crit Care Med. 2016 May;20(5):313-4. doi: 10.4103/0972-5229.182207.
9
Livedo reticularis: A review of the literature.网状青斑:文献综述
Indian Dermatol Online J. 2015 Sep-Oct;6(5):315-21. doi: 10.4103/2229-5178.164493.
10
Cutaneous metastasis as an initial presentation of a non-functioning pancreatic neuroendocrine tumor.皮肤转移作为无功能胰腺神经内分泌肿瘤的首发表现
World J Gastroenterol. 2015 Sep 7;21(33):9822-6. doi: 10.3748/wjg.v21.i33.9822.