Kim Joon Mo, Kim Se Young, Chin Hee Seung, Kim Hyun Ji, Kim Na Rae, Epidemiologic Survey Committee Of The Korean Ophthalmological Society On Behalf Of The
Department of Ophthalmology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, Korea.
Department of Ophthalmology and Inha Vision Science Laboratory, Inha University School of Medicine, Incheon 22332, Korea.
J Clin Med. 2019 Jul 22;8(7):1078. doi: 10.3390/jcm8071078.
This study was conducted using the database of the Korea National Health and Nutrition Examination Survey to determine whether age-related eye diseases such as cataract, glaucoma, diabetic retinopathy (DR), and age-related macular degeneration (AMD), are related to hearing loss. 12,899 participants ≥ 40 years of age were included. The weighted prevalence of diabetic retinopathy was not significantly different between the normal hearing group and hearing-impaired group, but the weighted prevalences of cataract, glaucoma, early AMD, and late AMD were significantly different in the two groups. The odds ratio for cataract in the hearing-impaired group was 1.373 (1.118-1.687). The odds ratios of glaucoma, DR, early AMD, and late AMD were not significantly different in the hearing-impaired group. Age was significantly associated with the presence of concurrent cataract and hearing impairment by 6.574-fold per decade. Significant factors that increased the risk of concurrent glaucoma and hearing impairment were age, male gender, and triglyceride. Age, ex-smoker, systolic BP elevation, BMI decline, and fasting blood sugar significantly predicted the presence of concurrent DR and hearing loss. In early AMD, age and triglyceride, and in late AMD, age and systolic BP elevations increased the risk of concurrent AMD and hearing impairment.
本研究利用韩国国民健康与营养检查调查数据库进行，以确定白内障、青光眼、糖尿病视网膜病变（DR）和年龄相关性黄斑变性（AMD）等与年龄相关的眼病是否与听力损失有关。研究纳入了12899名年龄≥40岁的参与者。正常听力组和听力受损组之间糖尿病视网膜病变的加权患病率无显著差异，但两组白内障、青光眼、早期AMD和晚期AMD的加权患病率存在显著差异。听力受损组白内障的优势比为1.373（1.118 - 1.687）。听力受损组青光眼、DR、早期AMD和晚期AMD的优势比无显著差异。年龄与并发白内障和听力障碍显著相关，每增加一个十年，风险增加6.574倍。增加并发青光眼和听力障碍风险的显著因素为年龄、男性性别和甘油三酯。年龄、既往吸烟者、收缩压升高、体重指数下降和空腹血糖显著预测了并发DR和听力损失的存在。在早期AMD中，年龄和甘油三酯，在晚期AMD中，年龄和收缩压升高增加了并发AMD和听力障碍的风险。
