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炎症性食物摄入与前瞻性观察队列中老年性听力损失的关系:来自普利亚萨卢斯研究的结果。

Relationship between Inflammatory Food Consumption and Age-Related Hearing Loss in a Prospective Observational Cohort: Results from the Salus in Apulia Study.

机构信息

Frailty Phenotypes Research Unit, "Salus in Apulia Study", National Institute of Gastroenterology "Saverio de Bellis", Research Hospital, Castellana Grotte, 70013 Bari, Italy.

Data Analysis Unit, National Institute of Gastroenterology "Saverio de Bellis", Research Hospital, Castellana Grotte, 70013 Bari, Italy.

出版信息

Nutrients. 2020 Feb 7;12(2):426. doi: 10.3390/nu12020426.

Abstract

UNLABELLED

Age related hearing loss (ARHL) affects about one third of the elderly population. It is suggested that the senescence of the hair cells could be modulated by inflammation. Thus, intake of anti- and pro-inflammatory foods is of high interest.

METHODS

From the MICOL study population, 734 participants were selected that participated in the 2013 to 2018 examination including hearing ability and from which past data collected in 2005/2008 was available. ARHL status was determined and compared cross-sectionally and retrospectively according to clinical and lifestyle data including food and micronutrient intake.

RESULTS

ARHL status was associated with higher age but not with education, smoking, relative weight (BMI), and clinical-chemical blood markers in the crossectional and retrospective analyses. Higher intake of fruit juices among ARHL-participants was seen cross-sectionally, and of sugary foods, high-caloric drinks, beer, and spirits retrospectively. No difference was found for the other 26 food groups and for dietary micronutrients with the exception of past vitamin A, which was higher among normal hearing subjects.

CONCLUSIONS

Pro-inflammatory foods with a high-sugar content and also beer and spirits were found to be assocated with positive ARHL-status, but not anti-inflammatory foods. Diet could be a candidate for lifestyle advice for the prevention of ARHL.

摘要

未加标签

年龄相关性听力损失(ARHL)影响约三分之一的老年人口。有人认为,毛细胞的衰老可以通过炎症来调节。因此,摄入抗炎和促炎食物具有重要意义。

方法

从 MICOL 研究人群中,选择了 734 名参加了 2013 年至 2018 年检查的参与者,包括听力能力,并从 2005/2008 年收集了过去的数据。根据临床和生活方式数据,包括食物和微量营养素摄入,确定 ARHL 状态,并进行横断面和回顾性比较。

结果

在横断面和回顾性分析中,ARHL 状态与年龄较高有关,但与教育、吸烟、相对体重(BMI)和临床化学血液标志物无关。在横断面研究中,ARHL 参与者的果汁摄入量较高,而在回顾性研究中,糖食、高卡路里饮料、啤酒和烈酒的摄入量较高。其他 26 种食物组和膳食微量营养素没有差异,但过去的维生素 A 除外,正常听力受试者的维生素 A 水平较高。

结论

发现具有高糖含量的促炎食物以及啤酒和烈酒与 ARHL 阳性状态相关,但抗炎食物则不然。饮食可能是预防 ARHL 的生活方式建议的候选方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b30/7071162/8c115bd91206/nutrients-12-00426-g001.jpg

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