Cadena Myrna, Kelman Todd, Marco Maria L, Pitesky Maurice
UC Davis School of Veterinary Medicine, Department of Population Health and Reproduction, Cooperative Extension, One Shields Ave, Davis, CA 95616, USA.
UC Davis, Department of Food Science and Technology, One Shields Ave, Davis, CA 95616, USA.
Foods. 2019 Jul 22;8(7):275. doi: 10.3390/foods8070275.
Foodborne pathogens such as that survive cleaning and disinfection during poultry processing are a public health concern because pathogens that survive disinfectants have greater potential to exhibit resistance to antibiotics and disinfectants after their initial disinfectant challenge. While the mechanisms conferring antimicrobial resistance (AMR) after exposure to disinfectants is complex, understanding the effects of disinfectants on in both their planktonic and biofilm states is becoming increasingly important, as AMR and disinfectant tolerant bacteria are becoming more prevalent in the food chain. This review examines the modes of action of various types of disinfectants commonly used during poultry processing (quaternary ammonium, organic acids, chlorine, alkaline detergents) and the mechanisms that may confer tolerance to disinfectants and cross-protection to antibiotics. The goal of this review article is to characterize the AMR profiles of in both their planktonic and biofilm state that have been challenged with hexadecylpyridinium chloride (HDP), peracetic acid (PAA), sodium hypochlorite (SHY) and trisodium phosphate (TSP) in order to understand the risk of these disinfectants inducing AMR in surviving bacteria that may enter the food chain.
在家禽加工过程中能在清洗和消毒后存活的食源性病原体是一个公共卫生问题，因为在消毒剂作用下存活的病原体在初次受到消毒剂挑战后，更有可能对抗生素和消毒剂产生耐药性。虽然接触消毒剂后产生抗菌耐药性（AMR）的机制很复杂，但了解消毒剂对处于浮游状态和生物膜状态的细菌的影响变得越来越重要，因为具有AMR和耐消毒剂的细菌在食物链中越来越普遍。本综述探讨了家禽加工过程中常用的各类消毒剂（季铵盐、有机酸、氯、碱性洗涤剂）的作用方式，以及可能赋予对消毒剂耐受性和对抗生素交叉保护的机制。这篇综述文章的目的是描述在受到十六烷基吡啶氯化物（HDP）、过氧乙酸（PAA）、次氯酸钠（SHY）和磷酸三钠（TSP）挑战后处于浮游状态和生物膜状态的细菌的AMR谱，以便了解这些消毒剂在可能进入食物链的存活细菌中诱导AMR的风险。
