免疫缺陷小鼠模型中的感染因子：Ⅰ型以色列放线菌在先天性无胸腺（裸）小鼠中的致病性。
Infectious agents in immunodeficient murine models: pathogenicity of Actinomyces israelii serotype I in congenitally athymic (nude) mice.
作者信息
Beaman B L, Gershwin M E, Maslan S
出版信息
Infect Immun. 1979 May;24(2):583-5. doi: 10.1128/iai.24.2.583-585.1979.
Abstract
Nude (Nu/Nu) and heterozygous (NU/+) mice were infected with Actinomyces israelii serotype I by either intranasal instillation or intravenous injection. Lung clearance data and 50% lethal dose values indicated that T-lymphocytes were not necessary for pulmonary clearance or prevention of systemic actinomycosis. However, T-lymphocyte deficiency may play a role in the localized cervicofacial form of actinomycosis.
摘要
裸鼠（Nu/Nu）和杂合子小鼠（NU/+）通过鼻内滴注或静脉注射感染了I型以色列放线菌。肺部清除数据和50%致死剂量值表明，T淋巴细胞对于肺部清除或预防全身性放线菌病并非必需。然而，T淋巴细胞缺乏可能在局限性颈面部放线菌病中起作用。
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引用本文的文献
本文引用的文献
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Experimental actinomycosis in mice. Study of pathogenesis.小鼠实验性放线菌病。发病机制研究。
Arch Pathol. 1970 Nov;90(5):391-402.
2
Lung response to congenitally athymic (nude), heterozygous, and Swiss Webster mice to aerogenic and intranasal infection by Nocardia asteroides.先天性无胸腺（裸）小鼠、杂合子小鼠和瑞士韦伯斯特小鼠对星形诺卡菌气源性感染和鼻内感染的肺部反应。
Infect Immun. 1978 Dec;22(3):867-77. doi: 10.1128/iai.22.3.867-877.1978.
3
Infectious agents in immunodeficient murine models: pathogenicity of Nocardia asteroides in congenitally athymic (nude) and hereditarily asplenic (Dh/+) mice.免疫缺陷小鼠模型中的感染因子：星形诺卡菌在先天性无胸腺（裸）小鼠和遗传性无脾（Dh/+）小鼠中的致病性。
Infect Immun. 1978 May;20(2):381-7. doi: 10.1128/iai.20.2.381-387.1978.
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