先天性无胸腺（裸）小鼠的罗德西亚锥虫感染
Trypanosoma rhodesiense infection in congenitally athymic (nude) mice.
作者信息
Campbell G H, Esser K M, Phillips S M
出版信息
Infect Immun. 1978 Jun;20(3):714-20. doi: 10.1128/iai.20.3.714-720.1978.
Abstract
Athymic nude mice (nu/nu), heterozygous litter mates (nu/+), and thymic reconstituted homozygous animals (nu/nu TxR) were infected with Trypanosoma rhodesiense. A reduced parasitemia and prolonged survival were observed in the nu/nu animals after infection and cure or after immunization with irradiated organisms. These studies indicate that resistance of mice to T. rhodesiense infection is relatively independent of thymic lymphocyte function.
摘要
将无胸腺裸鼠（nu/nu）、杂合子同窝小鼠（nu/+）和胸腺重建的纯合动物（nu/nu TxR）感染罗得西亚锥虫。在感染并治愈后或用经辐照的生物体免疫后，观察到nu/nu动物的寄生虫血症降低且存活时间延长。这些研究表明，小鼠对罗得西亚锥虫感染的抵抗力相对独立于胸腺淋巴细胞功能。
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