Widespread Report of Multiple Insecticide Resistance in s.l. Mosquitoes in Eight Communities in Southern Gombe, North-Eastern Nigeria.

BACKGROUND

Timely entomological and insecticide resistance monitoring is a key to generating relevant data for vector management. We investigated the insecticide susceptibility status of s.l. in eight rural farming communities in Southern Gombe, Nigeria.

METHODS

Overall, 3-5 days-old adult female mosquitoes reared from field-collected immature stages between September and November, 2014 were exposed to the diagnostic doses of pyrethroids, organophosphate and carbamate insecticides using the Center for Disease Control Bottle bioassay. The observatory knockdown time from exposure to each insecticide was recorded up to two hours. The dead mosquitoes were then identified morphologically and by molecular assays.

RESULTS

Mortality results showed resistance in s.l. populations to bendiocarb (2.3-100%), deltamethrin (39-70%), pirimiphos-methyl (65-95%), dichloro-diphenyl-trichloroethane (0-38.1%), permethrin (0-46.3%) and lambda-cyhalothrin (42.5-86.4%). The few cases of full susceptibility were observed from lamdacyhalothrin exposed population of s.l. in Banbam and Pantami respectively. 177 (45%) was significantly higher (P< 0.05) than 64 (16.3%), 34 (8.7%) and hybrid 78 (19.8%).

CONCLUSION

A strong evidence of widespread resistance in the major malaria vector species in Southern Gombe to all common classes of insecticides is a justification for the State Malaria Elimination Programme to consciously consider incorporating insecticide resistance management strategies into control programs in order to sustain the future of current control interventions.