Sakthivel Pirabu, Thakar Alok, Prashanth Arun, Arunraj Sreedharan Thankarajan, Kumar Rakesh, Kumar Rakesh
Department of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Indian J Nucl Med. 2020 Oct-Dec;35(4):372-373. doi: 10.4103/ijnm.IJNM_131_20. Epub 2020 Oct 21.
Somatostatin cell surface receptors are expressed on the peritumoral vessels of various benign and malignant neoplasms including angiofibromas. Positive initial uptake on positron emission tomography-computed tomography (PET/CT) imaging with Ga-labeled DOTANOC is noted in a patient with juvenile nasal angiofibroma (JNA), and the same is noted to be absent following complete surgical excision. Functional Ga-DOTANOC PET/CT may be an early useful tool for JNA residual/recurrence identification and precise postoperative surveillance.
生长抑素细胞表面受体在包括血管纤维瘤在内的各种良性和恶性肿瘤的瘤周血管上表达。在一名青少年鼻血管纤维瘤（JNA）患者中，使用镓标记的DOTANOC进行正电子发射断层扫描-计算机断层扫描（PET/CT）成像时，最初摄取呈阳性，而在完全手术切除后则未观察到同样情况。功能性镓-DOTANOC PET/CT可能是用于JNA残留/复发识别和精确术后监测的早期有用工具。
