Departments of Geriatric, The First Hospital of Quanzhou Affiliated to Fujian Medical University, Quanzhou, People's Republic of China.
Department of Cardiology, The Second Hospital Affiliated to Fujian Medical University, Quanzhou, People's Republic of China.
Clin Interv Aging. 2019 Jun 20;14:1119-1129. doi: 10.2147/CIA.S207665. eCollection 2019.
This study aims to analyze the prevalence of dyslipidemia and identify the cardiovascular disease (CVD) risk stratification among older adults living in Quanzhou, China's southeast coastal region, where the ancient Maritime Silk Road starts. A population-based cross-sectional survey of 2,018 adults was conducted in 60-98-year-old residents in Quanzhou from September 2016 to March 2018 using multistage stratified cluster random sampling. The 10-year CVD risk was also estimated by applying the Chinese model recommended by the Chinese Guidelines for Prevention of Cardiovascular Diseases. The overall prevalence of dyslipidemia among older adults was 56.8%. The prevalence of high total cholesterol (TC), high low-density lipoprotein cholesterol (LDL-C), low high-density lipoprotein cholesterol (HDL-C) and high triglyceride (TG) were 8.4%, 13.9%, 23.1% and 11.4%, respectively. The mean levels of TC, LDL-C, HDL-C and TG were 5.12±1.18, 3.37±0.81, 1.03±0.27 and 1.65±0.76 mmol/L, respectively. Older adults had low risk, moderate risk and high risk for CVD, which were 49.7%, 36.8% and 13.5%, respectively. Age, body mass index and abdominal obesity were significantly associated with the risk of increasing LDL-C levels and were positively correlated to CVD risk. The prevalence of high TC, high LDL-C, low HDL-C and high TG was relatively low among older adults in Quanzhou, but their lipid levels were high. Approximately half of the elderly adults had moderate or high CVD risk. The personalized primary prevention and control of CVD are recommended for elderly people to identify high-risk individuals.
本研究旨在分析血脂异常的流行情况,并确定中国东南沿海地区泉州的老年人的心血管疾病(CVD)风险分层情况,这里是古代海上丝绸之路的起点。2016 年 9 月至 2018 年 3 月,采用多阶段分层整群随机抽样方法,对泉州 60-98 岁居民进行了一项基于人群的横断面调查,共纳入 2018 名成年人。应用中国心血管病预防指南推荐的中国模型估算了 10 年 CVD 风险。老年人血脂异常的总体患病率为 56.8%。高总胆固醇(TC)、高低密度脂蛋白胆固醇(LDL-C)、低高密度脂蛋白胆固醇(HDL-C)和高三酰甘油(TG)的患病率分别为 8.4%、13.9%、23.1%和 11.4%。TC、LDL-C、HDL-C 和 TG 的平均水平分别为 5.12±1.18、3.37±0.81、1.03±0.27 和 1.65±0.76mmol/L。老年人 CVD 的低危、中危和高危分别为 49.7%、36.8%和 13.5%。年龄、体重指数和腹型肥胖与 LDL-C 水平升高的风险显著相关,与 CVD 风险呈正相关。泉州老年人 TC、LDL-C、HDL-C 和 TG 高的患病率相对较低,但血脂水平较高。大约一半的老年人存在中高危 CVD 风险。建议对老年人进行个体化的 CVD 一级预防和控制,以识别高危人群。