de la Fuente José, Estrada-Peña Agustín
SaBio, Instituto de Investigación en Recursos Cinegéticos (IREC-CSIC-UCLM-JCCM), Ronda de Toledo s/n, 13005 Ciudad Real, Spain.
Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA.
Vaccines (Basel). 2019 Jul 28;7(3):75. doi: 10.3390/vaccines7030075.
The prevention and control of vector-borne diseases is a priority for improving global health. Despite recent advances in the characterization of ectoparasite-host-pathogen molecular interactions, vaccines are not available for most ectoparasites and vector-borne diseases that cause millions of deaths yearly. In this paper, in response to the question of why new vaccines for the control of ectoparasite vectors have not been registered and commercialized, and to contribute developing new effective vaccines against ectoparasite vectors, we propose challenges and approaches to be addressed.
病媒传播疾病的预防和控制是改善全球健康的优先事项。尽管在体外寄生虫-宿主-病原体分子相互作用的表征方面取得了最新进展，但对于大多数每年导致数百万人死亡的体外寄生虫和病媒传播疾病而言，尚无可用疫苗。在本文中，为了回应为何用于控制体外寄生虫病媒的新型疫苗尚未注册和商业化这一问题，并为开发针对体外寄生虫病媒的新型有效疫苗做出贡献，我们提出了需要应对的挑战和方法。
