Jones A, Davies D H, Dove J R, Collinson M A, Brown P M
Health Centre, Gorseinon, Swansea.
Br Med J (Clin Res Ed). 1988 Jun 18;296(6638):1711-4. doi: 10.1136/bmj.296.6638.1711.
A screening programme for the identification of risk factors for coronary heart disease in all patients aged 25-55 years in a general practice population was studied. The identification of risk factors included measurement of obesity, blood pressure, hypercholesterolaemia, and urinalysis, together with questions about family history, cigarette smoking, alcohol intake, and lifestyle. The patients with identified risk factors were invited to attend a lifestyle intervention clinic organised by the practice nurses and run by the health visitors, with the help of the local authority dietitian. Of 2646 (62%) patients who attended for screening, 78 (64%) of the 121 shown to have a high cholesterol concentration experienced a drop in cholesterol concentration. The mean fall in cholesterol concentration in the 78 patients who showed a positive response to intervention was 1.1 mmol/l. The study was intended as a possible flexible model for screening for coronary heart disease in general practice that could be complemented rather than replaced by opportunistic screening. The issues of organisation, cost, manpower, nonattendance, and effectiveness in a busy general practice environment are discussed.
一项针对普通执业人群中所有25至55岁患者的冠心病危险因素筛查项目进行了研究。危险因素的识别包括对肥胖、血压、高胆固醇血症的测量以及尿液分析,同时还包括有关家族病史、吸烟、饮酒和生活方式的问题。识别出有危险因素的患者被邀请参加由执业护士组织、健康访视员主持并在当地政府营养师帮助下开展的生活方式干预诊所。在前来接受筛查的2646名(62%)患者中,121名胆固醇浓度高的患者中有78名(64%)胆固醇浓度有所下降。对干预有积极反应的78名患者胆固醇浓度平均下降了1.1 mmol/l。该研究旨在作为普通执业中冠心病筛查的一种可能的灵活模式,可通过机会性筛查进行补充而非替代。文中讨论了繁忙的普通执业环境中的组织、成本、人力、未就诊情况和有效性等问题。