Laboratory of Sensory Processing, Brain Mind Institute, Faculty of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Nat Rev Neurosci. 2019 Sep;20(9):533-546. doi: 10.1038/s41583-019-0200-y. Epub 2019 Jul 31.
Tactile sensory information from facial whiskers provides nocturnal tunnel-dwelling rodents, including mice and rats, with important spatial and textural information about their immediate surroundings. Whiskers are moved back and forth to scan the environment (whisking), and touch signals from each whisker evoke sparse patterns of neuronal activity in whisker-related primary somatosensory cortex (wS1; barrel cortex). Whisking is accompanied by desynchronized brain states and cell-type-specific changes in spontaneous and evoked neuronal activity. Tactile information, including object texture and location, appears to be computed in wS1 through integration of motor and sensory signals. wS1 also directly controls whisker movements and contributes to learned, whisker-dependent, goal-directed behaviours. The cell-type-specific neuronal circuitry in wS1 that contributes to whisker sensory perception is beginning to be defined.
面部触须的触觉感官信息为夜间在隧道中生活的啮齿动物（包括老鼠）提供了有关其周围环境的重要空间和纹理信息。触须来回移动以扫描环境（触须摆动），并且来自每个触须的触摸信号在与触须相关的初级体感皮层（wS1；桶状皮层）中引起稀疏的神经元活动模式。触须摆动伴随着去同步化的大脑状态和自发性和诱发性神经元活动的细胞类型特异性变化。触觉信息，包括物体纹理和位置，似乎通过运动和感觉信号的整合在 wS1 中进行计算。wS1 还直接控制触须运动，并有助于学习、依赖触须的、有目标的行为。有助于触须感觉感知的 wS1 中的细胞类型特异性神经元回路开始被定义。
