Geborek P, Lindoff B, Valind S O
Department of Rheumatology, University Hospital, Lund, Sweden.
Clin Physiol. 1988 Aug;8(4):427-32. doi: 10.1111/j.1475-097x.1988.tb00286.x.
A commercially available gas analyser was used to measure tension of oxygen (PO2) and carbon dioxide (PCO2) in synovial fluid samples after tonometry. Measured values of PCO2 were close to the expected (median difference 0.2 kPa, range -0.4 to 0.4) within the analysed concentration range of 4-10 kPa. No consistent difference between measured and expected values of PO2 were found for oxygen in the range 3-11 kPa (median difference 0.1 kPa, range -0.3 to 1.2). For oxygen tensions below 3 kPa, however, the measured values invariably overestimated the actual PO2, the errors ranging from 0.3 to 1.9 kPa, median 1.1. The importance of proper handling of samples was investigated and storage for 1 h at 0 degrees C in plastic syringes resulted in elevation of the PO2 levels measured (range of elevation 0.2 to 3.6 kPa, median 1.15), whilst no significant differences were found when stored in glass syringes. Within the limits stated, commercially available gas analysers may thus be used to investigate these parameters related to local tissue metabolism in effusive joint conditions.
在眼压测量后，使用市售的气体分析仪测量滑液样本中的氧分压（PO2）和二氧化碳分压（PCO2）。在4 - 10 kPa的分析浓度范围内，PCO2的测量值接近预期值（中位数差异为0.2 kPa，范围为 -0.4至0.4）。在3 - 11 kPa范围内，未发现PO2的测量值与预期值之间存在一致差异（中位数差异为0.1 kPa，范围为 -0.3至1.2）。然而，对于低于3 kPa的氧分压，测量值总是高估实际的PO2，误差范围为0.3至1.9 kPa，中位数为1.1。研究了样本妥善处理的重要性，在0摄氏度下于塑料注射器中储存1小时会导致所测PO2水平升高（升高范围为0.2至3.6 kPa，中位数为1.15），而储存在玻璃注射器中时未发现显著差异。因此，在规定的限度内，市售气体分析仪可用于研究渗出性关节疾病中与局部组织代谢相关的这些参数。
