Department of Systems Neuroscience, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.
Department of Neurology, University Medical Center Rostock, Rostock, Germany.
J Headache Pain. 2019 Aug 1;20(1):86. doi: 10.1186/s10194-019-1034-8.
Migraine is a common and severely disabling neurological disorder affecting millions of patients in Europe. Despite the availability of evidence-based national and international guidelines, the management of migraine patients often remains poor, which is often attributed to a low availability of headache specialists. The aim of this study was to investigate the adherence to national guidelines and to assess the possible potential of optimized therapy regimens in migraine patients.
We collected data of migraine patients presenting to our out-patient clinic via standardized questionnaires regarding headache, diagnostics and experience with previous treatments. We also assessed the efficacy of treatment started by our center.
1,935 migraine patients were included between 2010 and 2018. In the 12 months before consulting our headache clinic 89.5% of the patients had consulted a general practitioner and 74.9% had consulted a neurologist because of their migraine. Nevertheless, 50% of the patients underwent unnecessary diagnostics and 34.2% had not been treated according to evidence-based treatment guidelines. Out of 1,031 patients who had not been prescribed a preventative treatment 627 (60.8%) had in average 3 or more migraine attacks per month and thus qualified for a preventative treatment. These patients missed in the 3 months prior to consultation on average 5 work or school days. Initiating a preventative treatment was effective in 71.2% of the patients, that provided follow-up data.
Our data suggest, that many migraine patients to this day do not receive state-of-the-art therapy. Adherence to national and international European guidelines could improve the outcome in migraine patients. Future research should try to answer why guidelines are not followed.
偏头痛是一种常见且严重致残的神经系统疾病,影响着欧洲数以百万计的患者。尽管有基于证据的国家和国际指南,但偏头痛患者的管理往往仍然很差,这通常归因于头痛专家的短缺。本研究旨在调查对国家指南的遵守情况,并评估偏头痛患者优化治疗方案的可能潜力。
我们通过标准化问卷收集了在我们的门诊就诊的偏头痛患者的数据,内容涉及头痛、诊断和对先前治疗的经验。我们还评估了我们中心开始的治疗的疗效。
2010 年至 2018 年间,共纳入 1935 例偏头痛患者。在咨询我们头痛诊所前的 12 个月中,89.5%的患者因偏头痛咨询了全科医生,74.9%的患者咨询了神经科医生。然而,50%的患者接受了不必要的诊断,34.2%的患者没有按照基于证据的治疗指南进行治疗。在未开预防治疗的 1031 名患者中,有 627 名(60.8%)患者平均每月有 3 次或更多偏头痛发作,因此符合预防治疗的条件。这些患者在就诊前的 3 个月中平均缺课或旷工 5 天。在有随访数据的患者中,开始预防治疗对 71.2%的患者有效。
我们的数据表明,许多偏头痛患者至今仍未接受最先进的治疗。遵守国家和国际欧洲指南可以改善偏头痛患者的预后。未来的研究应该试图回答为什么不遵循指南。