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多糖的来源、提取及生物医学特性

Sources, Extraction and Biomedical Properties of Polysaccharides.

作者信息

Ullah Samee, Khalil Anees Ahmed, Shaukat Faryal, Song Yuanda

机构信息

Colin Ratledge Center for Microbial Lipids, Center for Functional Foods and Health, School of Agriculture Engineering and Food Science, Shandong University of Technology, Zibo 255049, China.

University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore, Lahore 54000, Pakistan.

出版信息

Foods. 2019 Aug 1;8(8):304. doi: 10.3390/foods8080304.

DOI:10.3390/foods8080304
PMID:31374889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6723881/
Abstract

In the recent era, bioactive compounds from plants have received great attention because of their vital health-related activities, such as antimicrobial activity, antioxidant activity, anticoagulant activity, anti-diabetic activity, UV protection, antiviral activity, hypoglycemia, etc. Previous studies have already shown that polysaccharides found in plants are not likely to be toxic. Based on these inspirational comments, most research focused on the isolation, identification, and bioactivities of polysaccharides. A large number of biologically active polysaccharides have been isolated with varying structural and biological activities. In this review, a comprehensive summary is provided of the recent developments in the physical and chemical properties as well as biological activities of polysaccharides from a number of important natural sources, such as wheat bran, orange peel, barely, fungi, algae, lichen, etc. This review also focused on biomedical applications of polysaccharides. The contents presented in this review will be useful as a reference for future research as well as for the extraction and application of these bioactive polysaccharides as a therapeutic agent.

摘要

近年来,植物中的生物活性化合物因其与健康相关的重要活性而备受关注,如抗菌活性、抗氧化活性、抗凝血活性、抗糖尿病活性、紫外线防护、抗病毒活性、降血糖等。先前的研究已经表明,植物中发现的多糖不太可能具有毒性。基于这些启发性的观点,大多数研究集中在多糖的分离、鉴定和生物活性上。大量具有不同结构和生物活性的生物活性多糖已被分离出来。在这篇综述中,对来自多种重要天然来源(如麦麸、橙皮、大麦、真菌、藻类、地衣等)的多糖的物理和化学性质以及生物活性的最新进展进行了全面总结。本综述还聚焦于多糖的生物医学应用。本综述中呈现的内容将作为未来研究以及这些生物活性多糖作为治疗剂的提取和应用的参考。