Rahman Mohammed Faisal, Panezai Muhammad Ajmal, Szerlip Harold M
Division of Nephrology, Baylor University Medical CenterDallasTexas.
Proc (Bayl Univ Med Cent). 2019 Jun 10;32(3):377-378. doi: 10.1080/08998280.2019.1613331. eCollection 2019 Jul.
Drug-induced lupus (DIL) is due to an autoimmune reaction to a drug with an estimated incidence of 15,000 to 30,000 cases every year in the US. Hydralazine is a well-known offender. Antinuclear antibody (ANA) is present in most cases, though four cases of ANA-negative DIL have been reported. In this report, we present another case of ANA-negative DIL secondary to hydralazine.
药物性狼疮（DIL）是由对药物的自身免疫反应引起的，在美国，其估计发病率为每年15000至30000例。肼屈嗪是一个众所周知的致病因素。大多数病例中存在抗核抗体（ANA），不过也有4例ANA阴性的药物性狼疮的报道。在本报告中，我们介绍了另一例继发于肼屈嗪的ANA阴性的药物性狼疮病例。
