An Juhyun, Yoon So Ra, Lee Jae Hyang, Kim Hyunyoung, Kim Oh Yoen
Department of Food Science and Nutrition, Dong-A University, Busan 49315, Korea.
Center for Silver-targeted Biomaterials, Brain Busan 21 Plus Program, Dong-A University, Busan 49315, Korea.
Clin Nutr Res. 2019 Jul 25;8(3):171-183. doi: 10.7762/cnr.2019.8.3.171. eCollection 2019 Jul.
We investigated weight loss effect of personalized diet education in overweight/obese Korean adults. Overweight/obese Korean adults (body mass index [BMI] ≥ 23 kg/m or waist circumference [WC] ≥ 90 cm for men, ≥ 85 cm for women) were recruited, and 40 participants who completed the 10-week intervention were finally included in the analyses. At first visit, study participants (small group with individual counseling) were educated for optimal diet by clinical dietitian, and checked for their compliance through telephone/text message every 1-2 week during the intervention. Anthropometric and biochemical parameters and dietary intake were investigated. Body weight, BMI, WC, and body fat mass were significantly reduced in whole participants. Hemoglobin A1c, insulin, and low-density lipoprotein cholesterol were also significantly decreased after the intervention. Total energy intake (EI) during the intervention was not significantly decreased compared to the baseline value, but the proportions of energy derived from macronutrients were within the ranges recommended by 2015 Dietary Reference Intake for Koreans. Based on actual EI, participants were classified into high-adherence (HA) (prescribed EI ± 25%, n = 29), low-adherence I (LA-I) (< 75% of prescribed EI, n = 7), and low-adherence II (LA-II) group (> 125% of prescribed EI, n = 4). Only HA group showed significant improvements in anthropometric parameters, glycemic control and lipid profile. Interestingly, LA-I group showed significant increases in glucose, insulin, C-peptide and insulin resistance. In conclusion, a shift from overweight/obesity to healthy weight can be accomplished by high adherence to personalized diet modification, not by EI reduction.
我们研究了个性化饮食教育对超重/肥胖韩国成年人的减肥效果。招募了超重/肥胖的韩国成年人（男性体重指数[BMI]≥23kg/m或腰围[WC]≥90cm，女性≥85cm），最终将40名完成10周干预的参与者纳入分析。在首次就诊时，由临床营养师对研究参与者（接受个体咨询的小组）进行最佳饮食教育，并在干预期间每1-2周通过电话/短信检查他们的依从性。对人体测量学和生化参数以及饮食摄入量进行了调查。所有参与者的体重、BMI、WC和体脂肪量均显著降低。干预后糖化血红蛋白、胰岛素和低密度脂蛋白胆固醇也显著下降。与基线值相比，干预期间的总能量摄入量（EI）没有显著降低，但宏量营养素的能量比例在《2015年韩国膳食参考摄入量》推荐的范围内。根据实际EI，参与者被分为高依从性（HA）组（规定EI±25%，n=29）、低依从性I（LA-I）组（<规定EI的75%，n=7）和低依从性II（LA-II）组（>规定EI的125%，n=4）。只有HA组在人体测量参数、血糖控制和血脂谱方面有显著改善。有趣的是，LA-I组的血糖、胰岛素、C肽和胰岛素抵抗显著增加。总之，通过高度依从个性化饮食调整而非减少EI，可以实现从超重/肥胖到健康体重的转变。
