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英国的脑肿瘤研究:现状与未来挑战。一份来自国家癌症研究所脑肿瘤临床研究小组的战略文件。

Brain tumor research in the United Kingdom: current perspective and future challenges. A strategy document from the NCRI Brain Tumor CSG.

作者信息

Kurian Kathreena M, Jenkinson Michael D, Brennan Paul M, Grant Robin, Jefferies Sarah, Rooney Alasdair G, Bulbeck Helen, Erridge Sara C, Mills Samantha, McBain Catherine, McCabe Martin G, Price Stephen J, Marino Silvia, Moyes Erica, Qian Wendy, Waldman Adam, Vaqas Babar, Keatley Debbie, Burchill Peter, Watts Colin

机构信息

Institute of Clinical Neurosciences, University of Bristol, Learning and Research Building, Southmead Hospital, Bristol.

Institute of Translational Medicine, University of Liverpool.

出版信息

Neurooncol Pract. 2018 Mar;5(1):10-17. doi: 10.1093/nop/npx022. Epub 2017 Aug 30.

Abstract

The National Cancer Research Institute (NCRI) is a partnership of charity and government research funders whose purpose is to improve health and quality of life by accelerating progress in cancer-related research through collaboration. Under this umbrella, the NCRI Brain Tumor Clinical Studies Group is focused on improving clinical outcomes for adult patients with brain and central nervous system tumors, including those with brain metastasis from other primary sites. This document discusses the current state of clinical brain tumor research in the United Kingdom and the challenges to increasing study and trial opportunities for patients. The clinical research priorities are defined along with a strategy to strengthen the existing brain tumor research network, improve access to tissue and imaging and to develop the future leadership for brain tumor research in the United Kingdom. This strategy document may serve as a framework for other organizations and countries.

摘要

国家癌症研究所(NCRI)是慈善机构和政府研究资助者的合作组织,其目的是通过合作加速癌症相关研究的进展,从而改善健康状况和生活质量。在此框架下,NCRI脑肿瘤临床研究小组专注于改善成年脑和中枢神经系统肿瘤患者的临床结局,包括那些有其他原发部位脑转移的患者。本文讨论了英国脑肿瘤临床研究的现状以及增加患者研究和试验机会所面临的挑战。确定了临床研究重点以及加强现有脑肿瘤研究网络、改善组织和影像获取途径并培养英国未来脑肿瘤研究领导力的策略。本战略文件可作为其他组织和国家的框架。

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