Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-Gu, Seoul, Republic of Korea.
PLoS One. 2019 Aug 6;14(8):e0220603. doi: 10.1371/journal.pone.0220603. eCollection 2019.
The black-blood (BB) technique was developed to suppress the signal from blood and cerebrospinal fluid (CSF) to provide improved depiction of vessel walls.
The aim was to compare three-dimensional turbo spin echo T1-weighted imaging (3D TSE T1WI) with or without two BB techniques (delay alternating with nutation for tailored excitation [DANTE], and improved motion-sensitized driven equilibrium [iMSDE]) for high-resolution magnetic resonance imaging (HR-MRI) of the vessel walls of intracranial arteries.
Prospective.
Fourteen healthy volunteers who underwent 3D T1WI for examination of intracranial vessel walls.
FIELD STRENGTH/SEQUENCE: 3 Tesla, 3D TSE T1WI (SPACE and BrainVIEW) and BB (DANTE and iMSDE).
SPACE with or without DANTE, and BrainVIEW with or without iMSDE, were acquired in each subject. Two neuroradiologists independently assessed image quality, vessel wall delineation, BB effect, CSF, and acceptability using visual scoring systems, and measured signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) in vessel walls, lumen, and CSF, while blinded to the presence and type of BB technique used.
Repeated measures ANOVA or Friedman tests were performed for the comparisons, followed by Bonferroni correction.
The 3T T1WI sequences without BB are significantly superior in vessel wall delineation (P = 0.001). Black CSF scores were lower in SPACE with DANTE than SPACE without DANTE, and in BrainVIEW without iMSDE than SPACE without DANTE (P < 0.001). However, there were no significant differences in BB effect, image quality, and acceptability between the four 3D T1WI sequences (p > .05). The SNRVessel wall, CNRWall-Lumen, and CNRWall-CSF were higher (all p < .001) on SPACE with and without DANTE than on BrainVIEW with and without iMSDE. SNRLumen were higher (all p < .001) on BrainVIEW with and without iMSDE than on SPACE with and without DANTE. SNRCSF was higher (all p < .001) on BrainVIEW with iMSDE than on SPACE with DANTE.
Both 3D TSE T1WI sequences were acceptable for intracranial vessel wall evaluation, with or without BB techniques. Therefore, BB techniques may not necessarily be required with 3D TSE T1WI with a long ETL and TR (below 1160 ms).
黑血（BB）技术的开发旨在抑制血液和脑脊液（CSF）的信号，以提供更好的血管壁描绘。
旨在比较三种三维涡轮自旋回波 T1 加权成像（3D TSE T1WI）加或不加两种 BB 技术（交替延迟激励的交替稳定进动[DANTE]和改进的运动敏感驱动平衡[ iMSDE]）用于颅内动脉血管壁的高分辨率磁共振成像（HR-MRI）。
前瞻性。
14 名健康志愿者接受颅内血管壁 3D T1WI 检查。
磁场强度/序列：3T，3D TSE T1WI（SPACE 和 BrainVIEW）和 BB（DANTE 和 iMSDE）。
每位受试者均采集 SPACE 加或不加 DANTE，以及 BrainVIEW 加或不加 iMSDE。两位神经放射学家使用视觉评分系统独立评估图像质量、血管壁描绘、BB 效果、CSF 和可接受性，并在不知道 BB 技术的存在和类型的情况下测量血管壁、管腔和 CSF 的信噪比（SNR）和对比噪声比（CNR）。
采用重复测量方差分析或 Friedman 检验进行比较，然后进行 Bonferroni 校正。
无 BB 的 3T T1WI 序列在血管壁描绘方面明显更优（P = 0.001）。SPACE 加 DANTE 的黑 CSF 评分明显低于 SPACE 不加 DANTE，而 SPACE 不加 DANTE 的黑 CSF 评分明显低于 SPACE 加 DANTE（P < 0.001）。然而，四种 3D T1WI 序列之间在 BB 效果、图像质量和可接受性方面无显著差异（p >.05）。SPACE 加和不加 DANTE 的 SNR 血管壁、CNR 壁-腔和 CNR 壁-CSF 均较高（均 P <.001），而 BrainVIEW 加和不加 iMSDE 的 SNR 血管壁、CNR 壁-腔和 CNR 壁-CSF 均较高（均 P <.001）。SPACE 加和不加 DANTE 的 SNR 管腔均较高（均 P <.001），而 BrainVIEW 加和不加 iMSDE 的 SNR 管腔均较高（均 P <.001）。SPACE 加 DANTE 的 SNRCSF 明显高于 BrainVIEW 加 iMSDE（P <.001）。
两种 3D TSE T1WI 序列均适用于颅内血管壁评估，加或不加 BB 技术。因此，对于 ETL 和 TR（低于 1160ms）较长的 3D TSE T1WI，可能不一定需要 BB 技术。
