Kim Han Ul, Na Kyeong Ik
Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.
Korean J Ophthalmol. 2019 Aug;33(4):379-385. doi: 10.3341/kjo.2018.0094.
To investigate the location of retinal nerve fiber layer defects (RNFLDs) in open-angle glaucoma and the differences in systemic and ocular factors between superotemporal and inferotemporal RNFLDs.
We performed a retrospective review of the 2008 to 2012 data from the Korea National Health and Nutrition Examination Survey. Subjects aged ≥19 years with an evaluable fundus photograph of at least one eye were enrolled, and open-angle glaucoma was diagnosed according to modified International Society of Geographical and Epidemiological Ophthalmology criteria. In subjects with open-angle glaucoma, locations of RNFLDs were evaluated, and systemic and ocular factors were compared between the bilateral superotemporal RNFLD group and bilateral inferotemporal RNFLD group.
A total of 534 subjects had open-angle glaucoma with RNFLDs. The unilateral inferotemporal region (25.8%) was the most common location for RNFLDs, followed by the unilateral superotemporal region (24.4%). Multivariate analysis revealed that hypertension was more significantly associated ( = 0.048) with the bilateral superotemporal RNFLD group than with the bilateral inferotemporal RNFLD group.
Superotemporal RNFLDs are more related to hypertension than are inferotemporal RNFLDs.
研究开角型青光眼视网膜神经纤维层缺损（RNFLDs）的位置，以及颞上和颞下RNFLDs在全身和眼部因素方面的差异。
我们对韩国国家健康与营养检查调查2008年至2012年的数据进行了回顾性分析。纳入年龄≥19岁且至少有一只眼睛有可评估眼底照片的受试者，并根据改良的国际地理和流行病学眼科学会标准诊断开角型青光眼。在开角型青光眼患者中，评估RNFLDs的位置，并比较双侧颞上RNFLD组和双侧颞下RNFLD组的全身和眼部因素。
共有534例开角型青光眼患者伴有RNFLDs。单侧颞下区域（25.8%）是RNFLDs最常见的位置，其次是单侧颞上区域（24.4%）。多因素分析显示，与双侧颞下RNFLD组相比，高血压与双侧颞上RNFLD组的相关性更强（P = 0.048）。
与颞下RNFLDs相比，颞上RNFLDs与高血压的关系更为密切。
