Zhao Fangkun, Yu Jiaming, Yan Qichang, Zhang Jinsong, Shi Mingyu
Department of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, The Key Laboratory of Lens in Liaoning Province, Shenyang, China.
Transl Vis Sci Technol. 2019 Aug 7;8(4):18. doi: 10.1167/tvst.8.4.18. eCollection 2019 Jul.
To evaluate the correlation between lens opacity degrees and phacoemulsification cumulated dissipated energy (CDE) values in patients with age-related cataract by applying 25-MHz panoramic ultrasound biomicroscopy (UBM).
This observational study was conducted in 227 patients (294 eyes) with age-related cataract. Patient ages ranged from 45 to 91 years. According to the lens images acquired by 25-MHz UBM, the objective indexes of lens opacity degrees were determined by using the ImageJ software. The correlation between lens opacity degrees (pixel units) and CDE values of phacoemulsification were mainly analyzed.
The means of measurements were as follows: preoperative LogMAR corrected distance visual acuity, anterior chamber depth, and central lens thickness was 1.10 ± 0.61, 2.52 ± 0.51, and 4.34 ± 0.60 mm, respectively. The mean 25-MHz UBM-measured lens opacity degree was 101.30 ± 19.70 pixel units, and the mean CDE value was 9.74 ± 9.10. There was a linear correlation between pixel units and the CDE value, as well as LogMAR corrected distance visual acuity ( = 0.38 and 0.50, respectively; both < 0.05). Age correlated with anterior chamber depth and lens thickness ( = -0.18 and 0.16, respectively; both < 0.05) but not with pixel units ( = -0.08, > 0.05).
The 25-MHz UBM has significant advantages in displaying the opacity feature of age-related cataract. The 25-MHz UBM combined with ImageJ software can be used to evaluate the opacity degree of age-related cataract quantitatively and may help predict the phacoemulsification parameters in cataract surgery.
Combination of the lens ultrasonic image and image analysis software enables researchers to evaluate lens opacity degree quantitatively and predict the parameters of phacoemulsification surgery.
应用25兆赫全景超声生物显微镜（UBM）评估年龄相关性白内障患者晶状体混浊程度与超声乳化累积消散能量（CDE）值之间的相关性。
本观察性研究纳入了227例（294只眼）年龄相关性白内障患者。患者年龄在45至91岁之间。根据25兆赫UBM获取的晶状体图像，使用ImageJ软件确定晶状体混浊程度的客观指标。主要分析晶状体混浊程度（像素单位）与超声乳化CDE值之间的相关性。
测量均值如下：术前LogMAR矫正远视力、前房深度和晶状体中央厚度分别为1.10±0.61、2.52±0.51和4.34±0.60毫米。25兆赫UBM测量的晶状体混浊程度均值为101.30±19.70像素单位，CDE值均值为9.74±9.10。像素单位与CDE值以及LogMAR矫正远视力之间存在线性相关性（分别为r = 0.38和0.50；均P < 0.05）。年龄与前房深度和晶状体厚度相关（分别为r = -0.18和0.16；均P < 0.05），但与像素单位无关（r = -0.08，P > 0.05）。
25兆赫UBM在显示年龄相关性白内障的混浊特征方面具有显著优势。25兆赫UBM联合ImageJ软件可用于定量评估年龄相关性白内障的混浊程度，并可能有助于预测白内障手术中的超声乳化参数。
晶状体超声图像与图像分析软件的结合使研究人员能够定量评估晶状体混浊程度并预测超声乳化手术参数。
