年龄相关性白内障中不同成像方法的晶状体混浊程度与超声乳化能量参数的相关性。

Correlation Between Degree of Lens Opacity and the Phacoemulsification Energy Parameters Using Different Imaging Methods in Age-Related Cataract.

机构信息

Department of Ophthalmology, The Fourth Affiliated Hospital of China Medical University, Eye Hospital of China Medical University, The Key Laboratory of Lens Research, Liaoning Province, Shenyang, China.

出版信息

Transl Vis Sci Technol. 2022 Mar 2;11(3):24. doi: 10.1167/tvst.11.3.24.

PURPOSE

To compare the correlation between degree of lens opacity and the phacoemulsification energy parameter in patients with age-related cataract as determined by slit lamp, 25-MHz ultrasound biomicroscopy (UBM), and Scheimpflug imaging (Pentacam) and to evaluate the application of these three methods to measuring lens opacification.

METHODS

This observational study was conducted in 319 patients (381 eyes) with different types of age-related cataract. The average age of patients was 67.3 ± 11.4 years. The degree of lens opacity acquired by slit lamp, 25-MHz UBM, and Pentacam was determined by the Lens Opacity Classification System III (LOCSIII), pixel units calculated by ImageJ, and lens density, respectively. We primarily analyzed and compared the correlation between lens opacity and the cumulative dissipated energy (CDE) values of phacoemulsification.

RESULTS

Cortical, nuclear, and posterior subcapsular (PSC) cataracts were evaluated as follows: LOCSIII grades 3.31 ± 1.42, 3.29 ± 1.49, and 0.91 ± 0.83; pixel units 120.91 ± 22.8, 93.2 ± 15.9, and 99.7 ± 13.0; and lens density 51.8 ± 31.2, 21.2 ± 6.10, and 53.3 ± 35.3, respectively. The CDE values were 12.1 ± 12.4, 13.5 ± 9.11, and 3.93 ± 1.96. In cortical cataract, there was a linear correlation among LOCSIII, pixel units, and CDE value (r = 0.560, r = 0.832, and r = 0.582, respectively; both P < 0.05), but lens density had no correlation with other parameters. In nuclear cataract, there was a linear correlation among LOCSIII, lens density, and CDE value (r = 0.747, r = 0.865, and r = 0.906, respectively; both P < 0.05), but pixel units had no correlation with other parameters. In PSC, only pixel units and LOCSIII showed a correlation.

CONCLUSIONS

The various imaging methods offered different advantages in terms of determining lens opacity, a feature related to types of age-related cataracts. Choosing the most suitable imaging method to evaluate lens opacification based on the type of age-related cataract is important for accurately predicting the phacoemulsification parameters for cataract surgery.

TRANSLATIONAL RELEVANCE

Determining the appropriate phacoemulsification strategy depends on quantitative analysis of the degree of lens opacity to reduce intraoperative and postoperative complications and to obtain the optimal postoperative visual outcome.

目的

比较裂隙灯、25MHz 超声生物显微镜（UBM）和 Scheimpflug 成像（Pentacam）评估年龄相关性白内障患者晶状体混浊程度与白内障超声乳化能量参数之间的相关性，并评估这三种方法在测量晶状体混浊中的应用。

方法

本观察性研究纳入了 319 例（381 只眼）不同类型年龄相关性白内障患者。患者平均年龄为 67.3±11.4 岁。采用 Lens Opacity Classification System III（LOCSIII）、ImageJ 计算的像素单位和晶状体密度分别评估裂隙灯、25MHz UBM 和 Pentacam 获得的晶状体混浊程度。主要分析并比较了晶状体混浊与白内障超声乳化累积耗散能量（CDE）值之间的相关性。

结果

皮质性、核性和后囊下白内障的 LOCSIII 分级分别为 3.31±1.42、3.29±1.49 和 0.91±0.83；像素单位分别为 120.91±22.8、93.2±15.9 和 99.7±13.0；晶状体密度分别为 51.8±31.2、21.2±6.10 和 53.3±35.3。CDE 值分别为 12.1±12.4、13.5±9.11 和 3.93±1.96。在皮质性白内障中，LOCSIII、像素单位和 CDE 值之间呈线性相关（r=0.560、r=0.832 和 r=0.582；均 P<0.05），但晶状体密度与其他参数无相关性。在核性白内障中，LOCSIII、晶状体密度和 CDE 值之间呈线性相关（r=0.747、r=0.865 和 r=0.906；均 P<0.05），但像素单位与其他参数无相关性。在后囊下白内障中，仅像素单位和 LOCSIII 之间存在相关性。