. Departamento de Clínica Médica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas - UNICAMP - Campinas (SP) Brasil.
. Divisão de Pneumologia, Instituto do Coração - InCor - Faculdade de Medicina, Universidade de São Paulo, São Paulo (SP) Brasil.
J Bras Pneumol. 2019 Aug 12;45(4):e20190122. doi: 10.1590/1806-3713/e20190122.
Bronchiectasis is a condition that has been increasingly diagnosed by chest HRCT. In the literature, bronchiectasis is divided into bronchiectasis secondary to cystic fibrosis and bronchiectasis not associated with cystic fibrosis, which is termed non-cystic fibrosis bronchiectasis. Many causes can lead to the development of bronchiectasis, and patients usually have chronic airway symptoms, recurrent infections, and CT abnormalities consistent with the condition. The first international guideline on the diagnosis and treatment of non-cystic fibrosis bronchiectasis was published in 2010. In Brazil, this is the first review document aimed at systematizing the knowledge that has been accumulated on the subject to date. Because there is insufficient evidence on which to base recommendations for various treatment topics, here the decision was made to prepare an expert consensus document. The Brazilian Thoracic Association Committee on Respiratory Infections summoned 10 pulmonologists with expertise in bronchiectasis in Brazil to conduct a critical assessment of the available scientific evidence and international guidelines, as well as to identify aspects that are relevant to the understanding of the heterogeneity of bronchiectasis and to its diagnostic and therapeutic management. Five broad topics were established (pathophysiology, diagnosis, monitoring of stable patients, treatment of stable patients, and management of exacerbations). After this subdivision, the topics were distributed among the authors, who conducted a nonsystematic review of the literature, giving priority to major publications in the specific areas, including original articles, review articles, and systematic reviews. The authors reviewed and commented on all topics, producing a single final document that was approved by consensus.
支气管扩张症是一种通过胸部高分辨率 CT 越来越多地诊断出的疾病。在文献中，支气管扩张症分为继发于囊性纤维化的支气管扩张症和不伴囊性纤维化的支气管扩张症，后者称为非囊性纤维化支气管扩张症。许多原因可导致支气管扩张症的发生，患者通常有慢性气道症状、反复感染和与该疾病一致的 CT 异常。2010 年发表了第一份关于非囊性纤维化支气管扩张症的诊断和治疗国际指南。在巴西，这是第一份旨在系统整理迄今为止在该主题上积累的知识的审查文件。由于缺乏各种治疗主题的推荐建议的证据，因此决定编写一份专家共识文件。巴西胸科协会呼吸感染委员会召集了 10 名在巴西具有支气管扩张症专业知识的肺病专家，对现有科学证据和国际指南进行了批判性评估，并确定了与理解支气管扩张症的异质性及其诊断和治疗管理相关的方面。确立了五个广泛的主题（发病机制、诊断、稳定期患者的监测、稳定期患者的治疗以及恶化期的管理）。在这一分组之后，将主题分配给作者，他们对文献进行了非系统性回顾，优先考虑特定领域的主要出版物，包括原始文章、综述文章和系统评价。作者审查并评论了所有主题，生成了一份由共识批准的最终文件。
