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用于缩窄性心包炎诊断和治疗的多模态成像

Multimodality imaging for the diagnosis and treatment of constrictive pericarditis.

作者信息

Chetrit Michael, Natalie Szpakowski Natalie, Desai Milind Y

机构信息

Department of Cardiovascular Medicine, Cleveland Clinic, Heart and Vascular Institute , Cleveland , OH , USA.

出版信息

Expert Rev Cardiovasc Ther. 2019 Sep;17(9):663-672. doi: 10.1080/14779072.2019.1657832. Epub 2019 Aug 23.

Abstract

: Constrictive pericarditis can result in debilitating congestive right heart failure and has been considered an important cause of morbidity and mortality in patients with cardiovascular disease. Multimodality imaging continues to play a fundamental role in the individual approach to diagnosis, management, and prognosis of patients with this clinical syndrome. : This article gives an overview of the clinical spectrum of constrictive pericardial diseases and the role of multimodality imaging in the diagnosis of constrictive pericarditis. There is a focus on the emerging role of cardiac magnetic resonance (CMR) for the diagnosis, management, and prognostication of patients with constrictive pericarditis based on more recent case series, retrospective and prospective studies, which have helped to define the role of CMR. : Advanced multimodality imaging assists with identification of both overt and subclinical pericardial inflammation. This allows the pericardiologist to recognize patients with potentially reversible disease, trial medical therapy, and thereby avoid mechanical removal of the pericardium. Further, pericardial characterization by CMR has provided novel information about the natural history of these pericardial conditions, which can help tailor therapy and improve prognosis.

摘要

缩窄性心包炎可导致使人衰弱的充血性右心衰竭,并且一直被认为是心血管疾病患者发病和死亡的重要原因。多模态成像在针对患有这种临床综合征的患者进行诊断、管理和预后评估的个体化方法中继续发挥着重要作用。本文概述了缩窄性心包疾病的临床范围以及多模态成像在缩窄性心包炎诊断中的作用。基于最近的病例系列、回顾性和前瞻性研究,重点关注心脏磁共振成像(CMR)在缩窄性心包炎患者的诊断、管理和预后评估方面的新作用,这些研究有助于明确CMR的作用。先进的多模态成像有助于识别明显的和亚临床的心包炎症。这使心包疾病专家能够识别出患有潜在可逆性疾病的患者,尝试药物治疗,从而避免进行心包的机械切除。此外,CMR对心包的特征描述提供了有关这些心包疾病自然病程的新信息,这有助于调整治疗方案并改善预后。

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