Aminoshariae Anita, Kulild James C
Department of Endodontics, School of Dental Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
Department of Endodontics, UMKC School of Dentistry, Kansas City, Missouri, USA.
Aust Endod J. 2020 Apr;46(1):123-129. doi: 10.1111/aej.12370. Epub 2019 Aug 26.
The purpose of this systematic review was to qualify and quantify the evidence regarding the effect of extruded sealers on endodontic treatment outcomes. Two reviewers independently conducted a comprehensive literature search. The EMBASE, MEDLINE, Cochrane, PubMed databases, bibliographies, grey literature of all relevant articles and textbooks were searched. Six articles met the inclusion criteria with a moderate risk of bias and were analysed for qualitative and quantitative synthesis. There was moderate-certainty evidence that sealer extrusion can contribute to non-healing outcomes, 95% confidence interval, risk ratio 1.32 (1.12-1.54) and P < 0.05. This indicates that the current authors are somewhat confident the true effect is likely to be close to the estimate of the effect. Sealer extrusion had a 32% higher risk of contributing to a non-healing outcome than no extrusion. However, well-conducted research would need to be conducted to confirm this causality claim.
本系统评价的目的是对有关挤压式封闭剂对根管治疗结果影响的证据进行定性和定量分析。两名评价者独立进行了全面的文献检索。检索了EMBASE、MEDLINE、Cochrane、PubMed数据库、参考文献以及所有相关文章和教科书的灰色文献。6篇文章符合纳入标准，存在中度偏倚风险，并进行了定性和定量综合分析。有中度确定性证据表明，封闭剂挤压可能导致治疗不愈合，95%置信区间，风险比1.32（1.12 - 1.54），P < 0.05。这表明当前作者在一定程度上确信真实效应可能接近效应估计值。与未发生挤压相比，封闭剂挤压导致治疗不愈合的风险高32%。然而，需要进行严谨的研究来证实这种因果关系。
