School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Phytother Res. 2019 Oct;33(10):2649-2660. doi: 10.1002/ptr.6465. Epub 2019 Aug 28.
Metabolic syndrome (MS) is a highly prevalent health problem worldwide and is associated with different risk factors, including hyperglycemia, dyslipidemia, hypertension, and obesity. This condition increases the risk of developing type II diabetes mellitus and cardiovascular problems. The MS is one of the most important health concerns in industrialized countries and mainly results from a sedentary lifestyle, high levels of subjective stress, and unhealthy diets. Nowadays, the identification of appropriate health care approaches, such as herbal medicines, with fewer side effects is more favorable, especially with regard to the adverse effects of chemical drugs. Aloe barbadensis Miller known as Aloe vera is a useful plant with two major parts, including leaves that contain high concentrations of anthraquinone compounds and a clear gel. The gel is used as a food with several beneficial properties, such as antiinflammatory, antioxidant, antiviral, antibacterial, and wound-healing features. Other effects of A. vera, such as its lipid-lowering, antihypertensive, antidiabetic, antiobesity, and cardioprotective impacts, have been demonstrated in several studies. The present study was conducted to review the evidence on the pharmacological effects of A. vera on the different components of MS.
代谢综合征（MS）是一种在全球范围内普遍存在的健康问题，与多种危险因素相关，包括高血糖、血脂异常、高血压和肥胖。这种情况会增加患 2 型糖尿病和心血管问题的风险。MS 是工业化国家最重要的健康关注点之一，主要是由于久坐的生活方式、高水平的主观压力和不健康的饮食。如今，人们更倾向于寻找合适的医疗保健方法，如副作用较少的草药，尤其是考虑到化学药物的不良反应。Aloe barbadensis Miller 被称为 Aloe vera，是一种具有两种主要部分的有用植物，包括含有高浓度蒽醌化合物的叶子和一种透明的凝胶。凝胶被用作具有多种有益特性的食品，如抗炎、抗氧化、抗病毒、抗菌和伤口愈合特性。A. vera 的其他作用，如降血脂、降血压、降血糖、抗肥胖和心脏保护作用，已在多项研究中得到证实。本研究旨在综述 A. vera 对 MS 不同成分的药理作用的证据。
