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苯丙素类化合物及其衍生物:生物活性及其在食品、医药和化妆品工业中的作用。

Phenylpropanoids and its derivatives: biological activities and its role in food, pharmaceutical and cosmetic industries.

机构信息

Department of Microbiology, Maharshi Dayanand University, Rohtak, Haryana, India.

Department of Pharmaceutical sciences, Maharshi Dayanand University, Rohtak, Haryana, India.

出版信息

Crit Rev Food Sci Nutr. 2020;60(16):2655-2675. doi: 10.1080/10408398.2019.1653822. Epub 2019 Aug 28.

DOI:10.1080/10408398.2019.1653822
PMID:31456411
Abstract

Phenylpropanoids and their derivatives are plant secondary metabolites widely present in fruits, vegetables, cereal grains, beverages, spices and herbs. They are known to have multifaceted effects which include antimicrobial, antioxidant, anti-inflammatory, antidiabetic, anticancer activities and as well as exhibits renoprotective, neuroprotective, cardioprotective and hepatoprotective effects. Owing to their antioxidant, antimicrobial and photoprotective properties, these compounds have wide application in the food (preservation, packaging films and edible coating), pharmaceutical, cosmetic and other industries such as textile (colorant), biofuel (antioxidant additive) and sensors (sensing biologically relevant molecules). Phenylpropanoids are present in commercially available dietary supplements and skin care products. In this review, we have presented the current knowledge on the biosynthesis, occurrence, biological activities of phenylpropanoids and their derivatives, along with the mechanism of action and their potential applications in various industries.

摘要

苯丙素类化合物及其衍生物是广泛存在于水果、蔬菜、谷物、饮料、香料和草药中的植物次生代谢物。它们具有多方面的作用,包括抗菌、抗氧化、抗炎、抗糖尿病、抗癌活性,以及具有肾保护、神经保护、心脏保护和肝脏保护作用。由于其抗氧化、抗菌和光保护特性,这些化合物在食品(保鲜、包装薄膜和可食用涂层)、制药、化妆品和其他行业(如纺织(着色剂)、生物燃料(抗氧化添加剂)和传感器(感测生物相关分子))中有广泛的应用。苯丙素类化合物存在于市售的膳食补充剂和护肤品中。在这篇综述中,我们介绍了苯丙素类化合物及其衍生物的生物合成、存在、生物活性、作用机制以及它们在各个行业的潜在应用的最新知识。

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