Ariadi Ariadi, Jamsari Jamsari, Yanwirasti Yanwirasti, Siregar Muhammad Fidel Ganis, Yusrawati Yusrawati
Fertility and Reproductive Endocrinology Division, Obstetrics and Gynecology Department, Medical Faculty of Andalas University, Padang, West Sumatera, Indonesia.
Agriculture Faculty of Andalas University, Padang, West Sumatera, Indonesia.
Open Access Maced J Med Sci. 2019 Jul 14;7(13):2084-2087. doi: 10.3889/oamjms.2019.625. eCollection 2019 Jul 15.
Menopause is a condition where women had not experienced menstruation for 12 consecutive cycles. At menopause period, there is alteration in women reproductive cycle where estrogen decreased and lipid status altered.
This study is aimed to understand the association of estrogen level and lipid status in menopause women.
This study was an observational study with cross-sectional design underwent in Obstetrics and Gynecology Polyclinic Dr M. Djamil Hospital, Padang to examine estrogen level and lipid level in 107 menopause women aged between 40-60 years old. The study was conducted for 6 months. The relationship between estrogen level and lipid profile was done using correlation test and p-value < 0.05 is significant.
There was no significant correlation between estrogen and total cholesterol (p = 0.146), LDL (p = 0.496), HDL (p = 0.172) and triglyceride (p = 0.296) in menopause women. There was negative correlation between estrogen with total cholesterol (r = -0.141; p = 0.146), HDL (r = -0.133; p = 0.172) and triglyceride (r = -0.1; p = 0.296) and a little positive correlation with LDL (r = 0.06; p = 0.496). Estrogen levels are not related to total Cholesterol, LDL, HDL, and triglyceride in menopause women.
Estrogen levels did not correlate with lipid status in menopause women in West Sumatera.
更年期是指女性连续12个周期未经历月经的一种状况。在更年期期间，女性的生殖周期会发生变化，雌激素水平下降，脂质状态改变。
本研究旨在了解更年期女性雌激素水平与脂质状态之间的关联。
本研究是一项横断面设计的观察性研究，在巴东M. 贾米尔博士医院妇产科门诊进行，以检测107名年龄在40 - 60岁之间的更年期女性的雌激素水平和脂质水平。该研究持续了6个月。使用相关性检验分析雌激素水平与脂质谱之间的关系，p值<0.05具有显著性。
更年期女性的雌激素与总胆固醇（p = 0.146）、低密度脂蛋白（p = 0.496）、高密度脂蛋白（p = 0.172）和甘油三酯（p = 0.296）之间无显著相关性。雌激素与总胆固醇（r = -0.141；p = 0.146）、高密度脂蛋白（r = -0.133；p = 0.172）和甘油三酯（r = -0.1；p = 0.296）呈负相关，与低密度脂蛋白呈微弱正相关（r = 0.06；p = 0.496）。更年期女性的雌激素水平与总胆固醇、低密度脂蛋白、高密度脂蛋白和甘油三酯无关。
在西苏门答腊，更年期女性的雌激素水平与脂质状态不相关。
