Tavakoli Ahmad, Karbalaie Niya Mohammad Hadi, Bokharaei-Salim Farah, Farahmand Mohammad, Izadi Morteza, Dorostkar Ruhollah, Keyvani Hossein
Department of Medical Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran.
Med J Islam Repub Iran. 2019 May 8;33:40. doi: 10.34171/mjiri.33.40. eCollection 2019.
Military populations are more prone to respiratory infections worldwide. There is a dearth of research about the role of viral pathogens in the etiology of respiratory infections in military trainees in Iran. Hence, we aimed to investigate the molecular epidemiology and clinical symptoms of respiratory viruses among this population. This cross-sectional study was performed on 400 military trainees with symptoms of respiratory infection, referred to the military medical clinic center in the basic military training camp of the General Staff of the Armed Forces of the Islamic Republic of Iran. Nucleic acid extraction from the throat or nasopharyngeal swab samples was performed by an automated extraction system. The extracts were then analyzed by the CLART® PneumoVir array system for the detection of respiratory viruses. All military trainees were male, aged between 18 and 57 years (mean: 21.69 years). Sore throat (75.5%), rhinorrhea (63.2%), cough (59.2%), fever (59.2%), and nasal congestion (50.5%) were amongst the most common symptoms. Overall, viral pathogens were detected in a total count of 124 (31%). The most commonly detected viruses were rhinovirus (7.2%), respiratory syncytial virus A (7.2%) and influenza B virus (6%). This study was an important first step for understanding the etiological role of viral pathogens in respiratory infection among military trainees population in Iran. Our results indicated that rhinovirus, respiratory syncytial virus A and influenza B virus are important viral pathogens causing respiratory infection in military trainees, respectively. However, further multi-center studies with larger sample size are strongly recommended to confirm our findings.
在全球范围内，军人更容易患呼吸道感染。关于病毒病原体在伊朗军事学员呼吸道感染病因中的作用，缺乏相关研究。因此，我们旨在调查该人群中呼吸道病毒的分子流行病学和临床症状。这项横断面研究是对400名有呼吸道感染症状的军事学员进行的，这些学员被转诊至伊朗伊斯兰共和国武装部队总参谋部基础军事训练营的军事医疗诊所中心。通过自动提取系统从咽喉或鼻咽拭子样本中提取核酸。然后，提取物通过CLART® PneumoVir阵列系统进行分析，以检测呼吸道病毒。所有军事学员均为男性，年龄在18至57岁之间（平均：21.69岁）。喉咙痛（75.5%）、流鼻涕（63.2%）、咳嗽（59.2%）、发烧（59.2%）和鼻塞（50.5%）是最常见的症状。总体而言，共检测到124例（31%）病毒病原体。最常检测到的病毒是鼻病毒（7.2%）、呼吸道合胞病毒A（7.2%）和乙型流感病毒（6%）。这项研究是了解病毒病原体在伊朗军事学员呼吸道感染病因学中作用的重要第一步。我们的结果表明，鼻病毒、呼吸道合胞病毒A和乙型流感病毒分别是导致军事学员呼吸道感染的重要病毒病原体。然而，强烈建议进行进一步的多中心、大样本量研究以证实我们的发现。
